Methylephedrine (metoprolol)

METOPROLOL (Metoprolol) *.

  (#) -1 - (Izopropilamino) -3-[parameters (metoksietil) phenoxy] -2-propanol.

     Synonyms : Betalok, Bloksan, Spesikor, Beloc, Betaloc, Blocksan, Lopressor, Veobloc, Opresol, Selopral, Specior and others.

     Available in a bitartrata.

     Is selective (kardioselektivnym) b 1-adrenoblokatorom. Inner simpatomimeticheskoy activity is not.

     As of close to atenolol (see).

     If ingestion is rapidly absorbed. The half of the blood plasma of 3 to 5 h, but the effect on blood pressure and heartbeat frequency is (after taking into one 100 mg) for 12 h. Provided through the kidneys in the form of metabolites.

     Applied with hypertension, strokes, infants (supraventrikulyarnoy tachycardia, fibrillation, ventricular arrythmia) with gipertireoidizme, to prevent repeat heart attacks.

     Inside and applied intravenously.

     Inside designate dose of 100 to 200 mg / day in 2 - 3 admission. If necessary, increase the dose, and in hypertensive disease in the event of inadequate performance appoint more antigipertenzivnye other means.

     Intravenous (for pressing reasons) imposed from 5 mg (at the rate of 1 to 2 mg per minute); If necessary, re-enter at intervals of 5 minutes and 10 doses of 15 mg. Supportive therapy appointment to the interior of the drug dose of 200 mg per day.

     Possible side effects, precautions and contraindications are the same as other b-adrenoblokatorov. Intravenous there should be methylephedrine if systolic AD is less than 110 mm Hg. Art. Patients who are bronhospasticheskimi phenomena to the simultaneous appointment of b-adrenostimuliruyuschih drugs.

     Method of production : tablets of 50 mg and 100 in a package of 30; 100 and 200 pieces; 1% solution of 5 ml ampoules in a package of 10 vials. Storage : List B. When temperature is not above + 25 'C.

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