Metindion (methindionum)


METINDION (Methindionum). 2-Metilamino- etilindandiona 2--1 3 hydrochloride.
     White or white with yellow or white crystalline powder donations. The easily soluble in water and alcohol.
     Metindion derives indandiona. By building close to the anticoagulant fenilinu (see), but the difference is that to aminoproizvodnym and antikoagulyantnogo do not have. On pharmacological properties of a selective force convulsants funds. Bush sedated and is not offered.
     Applied to large forms of epilepsy with toniko- klonicheskimi and psychomotor epileptic. Showed well as depression, and senestopaticheskih ipohondricheskih disorders in patients with epilepsy.
     Assign inside after eating adult to 0.25 g per reception. Epilepsy Patients with frequent seizures take medication to 6 times a day at intervals of 1, 5, 2 h (daily doses of 1, 5 g). In rare fits designate the same time dose of 4 - 5 times a day (daily doses of 1 to 1, 25 g).
     If necessary metindion combine with phenobarbital and benzodiazapine drugs (sibazonom, nitrazepamom).
     Switching treatment metindionom as ANTIEPILEPTICS switching to other drugs, should be gradual, consistent with lower doses of drugs and increased doses metindiona.
     When mental violations in patients epilepsy drug appoint 0.25 g four times a day.
     The drug is usually well. In some cases, there are dizziness, nausea, tremor fingertips; In these cases, lower dose.
     The drug is contraindicated in expressed great anxiety and tension.
     Product : pills to 0.25 g.
     Storage : List B. In dry, the dark spot.

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