MEPROTAN (Meprotanum).

     Dikarbamat propilpropandiola 2-methyl-1, 3.

     Synonyms : Meprobamat, Andaxin, Aneural, Biobamat, Equanil, Gadexyl, Harmonin, Mepavlon, Meprobamatum, Meprobamate, Meproban, Meprospan, Miltown, Nephentine, Pankalma, Pertranquile, Procalmadiol, Quanil, Restenil, Sedanyl, Sedazil, Sedral, Tensonal, Tranquil, Tranquilan, Tranquiline, Tranquisan and others.

     The white crystalline powder. Little is soluble in water, easy-to alcohol.

     Meprobamate (Meprobamat) is typically tranquilizers (<small> tranquilizers). A synthesized searching central muscle. The first product of the team was 3-(ortho toloksi) -1, 2, nitrated, or mianezin (synonyms : Mephenesin, Tolserol etc.), but due to the short duration, low efficiency in the ingestion and the high toxicity lost value as medicine.

     Meprobamate proved to be more active, effective when administered and much less toxic. Along with miorelaksiruyuschim actions related to the braking transfer excitation inserted in the spinal cord neurons, cheeks and the hypothalamus, he has a general calming effect on the central nervous system, increases the effect of sleeping pills and anaesthetics, has protivosudorozhnoy activity.

     At department vegetative nervous system Meprobamate expressed no influence; No effect on the cardiovascular system, respiration, smooth muscle; Several lowers the body temperature.

     Meprobamate effective as a means of calming mainly in the state of nervousness and TV and has been in wide use in medical practice.

     Meprobamate applied to the state of nervousness and gets underway with irritability, excitation, anxiety, fear, emotional tension, disturbance of sleep disorders in conditions of severe somatic diseases, and diseases involving increased muscle tone, with the disease of joints with muscle cramps .

     In psychiatric practice in acute Disorders able to be productive mental disorders Meprobamate ineffective.

     As a means of soothing can have beneficial effects in vegetative dystonia, pre-syndromic, climax, the primary form of hypertension, stomach ulcers, skin disorders and others with sleep disorders Meprobamate can be used alone and in combination with drugs means.

     In surgical practice Meprobamate used in the preparation of operational intervention to reduce the fear of the operation, for some downward muscle strain.

     Assign inside (after eating) tablets dose of 0.2 - 0.4 g per reception 2 to 3 times a day. Daily intake if necessary, may be increased to 2 to 3 g. The insomnia are 0,2 - 0,4 - 0,6 g at night.

     Higher doses for adults inside : single 0.8 g daily 3 g.

     Children drug designate smaller doses : at the age of 3 to 8 years in the 0.1 - 0.2 g 2 - 3 times a day, 8 to 14 years - 0.2 g 2 - 3 times a day. The course of treatment lasts, on average, 1 to 2 months. When a treatment dose should be reduced gradually, as the sudden removal of the drug could lead to a renewed fear, insomnia, etc.

     Meprobamate is usually well tolerated. In individual cases, there may be allergic (skin deterioration, etc.) and diarrhoeal phenomenon, heightened mood, a sense of gravity in the limbs, coordinating traffic violation. These phenomena are usually routed through 1 - 2 days after preparation.

     Those receiving Meprobamate should not be allowed to drive a transport and carry out other work that requires quick mental and motor responses.

     In some cases, admission is meprotana euphoria. There are reports of the possibility of adjusting to a drug and psychological dependence. Treatment meprotanom should take place under medical supervision.

     Product : 0.2 grams of pills in a package of 20 pieces.

     Storage : List B. The well ukuporennoy packaging.

Materials allowed to copy only with the active hyperlink to the handbook of medicines