MAGNESIUM SULFAT (Magnesii sulfas).

     Synonyms : bitter salt, Magnesium sulfuricum, Sal amarum.

     Clear Prismatic crystals vyvetrivayuschiesya in the air, easily soluble in water (1:1 in the cold and Z, Z : 1 in boiling); Practically insoluble in alcohol. Aqueous solutions are gorko- salty taste.

     Solutions for injection (pH 6, 2, 8, 0) in sterile 100 'C for 30 min, with 120' C for 8 min.

     Magnesium sulfate has a multifaceted impact on the body. When ingestion poorly absorbed, acts as a laxative means, like sodium sulfate, and also provides choleretic effect because of the reflexes, nerve irritation caused by the end of duodenal mucosal gut.

     When parenteral introduction of magnesium sulfate has a soothing effect on the central nervous system. Depending on the dose may be a sedative, sleeping pills or drug effect.

     One of the characteristics of magnesium sulfate is a depressant effect on the nerve-muscle transfer. When parenteral introduction, especially in high doses, it can kurarepodobnoe effect.

     The drug reduces anxiety respiratory centre, large parenteral dosage in a can easily cause respiratory paralysis. Blood pressure drops slightly in the overall calming effect of the drug; This effect is more pronounced in hypertensive disease.

     Provided magnesium sulfate kidneys, in the process providing enhanced Diurez.

     Antagonists of magnesium ions is calcium ions. Reducing detained while calcium in the blood by increasing of magnesium. Soli Pascal shall use as a pharmaceutical in the administration of magnesium sulfate.

     Using magnesium sulfate as slabitelnogo and choleretic means, and sometimes soothing, skin and protivosudorozh leg. As the drug does not apply because of the low latitude of (drug doses easily lead to the paralysis of the respiratory center), but can be used to enhance the action of drugs and analgetikov.

     As laxative appointed interior (overnight or for shock-ZO minutes before eating) for adults 10 to 30 grams in 1 / 2 cup water, children - at the rate of 1 g to 1 year of life. In chronic constipation may apply enema (100 ml of 20 - 30% solution).

     As choleretic are inside the cafeteria spoon on 1 20-25% Kemerovo thief three times a day; They also provide intelligent sensing probe through a warm magnesium sulfate solution (50 ml 25%, or 100 ml of 10% solution).

     As skin (and to some extent antihypertensive) tool sometimes used in the treatment of early stage hypertension. Enter intramuscularly to 5 -10-20 ml 20% or 25% solution of magnesium sulfate. The course of treatment-15 - 20 inektsny (daily). Along with the reduction in AD may experience some reduction in symptoms strokes. Automatic Systems reception inside the small doses (1, 2 g per 1 / 2 cup water PCP) inoga also contributed to the improvement of patients and some slowing atherosclerosis. In PNDS crises impose intramuscularly or intravenously (slowly!) 10-20-20 mL of 25% magnesium sulfate solution.

     When pain in the muscles give birth to a 5 - 10-20 ml 25% Kemerovo thief, sometimes in combination with analgeziruyuschimi means; While you need to consider the ability of oppression uterine musculature uterus, which may require the use rodostimuliruyuschih funds. When it pozd toxaemia pregnant impose intramuscularly to 10-20 ml 25% Kemerovo thief 1 -2 times daily. Sometimes it imposed concurrently with neyrolepticheskimi means.

     When convulsions give muscle to a 5--10 25% 20 ml solution.

     When lead colic and delay urination used as a means of spasmolytic; Give muscles (5 - 10-20 ml 10% solution), in the vein (5 to 10 ml of 5% solution) or by enema.

     Magnesium sulfate used as the antidote. When poisoning soluble salts of barium washed stomach 1% solution of magnesium sulfa either give into 20 to 25 grams in a glass of water (for education neyadovitogo barium sulfate). When poisoning by mercury, arsenic, lead injected (5 - 10-10 ml of 5% solution).

     Parenteral magnesium sulfate used with caution, given consumes about depressed respiration. In veins solutions imposed slowly. In ugnete breath of introducing non-calcium chloride (5, 10 ml 10% solution), are breathing oxygen or karbogen, artificial ventilation to the lungs.

     Method of issuance : powder; 20% or 25% solution in ampoules to 5; 10 and 20 ml.

     Storage : Keep in horisho ukuporennoy packaging.

     R p. : Sol. Ma gnesii sulfatis 25% 10 ml

     D.t.d. N. 3 in ampull.

     S. On May 10 ml of muscle

     R p. : Ma gnesii sulfatis 30.0

     D. S. At one time, assigned to 1 / 2 cup warm water (laxative)

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