Legalon (legalon)

LEGALON (Legalon) *.

     The preparation containing active substances fruit plants Silybum spotted (pestro islands; L. Silybum marianum).

     In 1969 these fruits (Fructus Cardui mariae) allocated flavonoidnyh group of compounds that have gepatotropnoe effect. This group of compounds has been identified as Oleum (Silimarin). In the future from silimarina been allocated three separate isomeric compounds : silibinin, and silidianin silikristin. All three compounds are fenilhromanonovuyu structure and in varying degrees gepatoprotektornoy activity.

     Legalon 'is a summary of preparation containing Oleum, silibinin and fruit extract Silybum spotted.

     Close-ended and of drugs manufactured in different countries under different names : Karsil, Apihepar, Carsil, Dorogan, Duricol, Hepadestal, Laragon, Silarine, Silgen, Silibancol, Silimarin, Silybin, Silymarin, Silymarol, Somatron and others.

     Legalon issued in the form of pellets (legalon-70) containing 70 mg silimarina with no less than 30 mg 90 mg silibinina fruit extract Silybum spotted; A capsules (legalon-140) containing 140 mg silimarina with no less than 60 mg silibinina 180 mg extract of the fruit Silybum spotted; a suspension (legalon- suspension), containing 100 grams silimarina 1 g of not less than 0.43 g silibinina 1, 3 g zkstrakta fruit Silybum spotted.

     Applied legalon with acute hepatitis (toxic) for maintenance therapy in chronic liver diseases and cirrhosis of liver.

     Gepatoprotektornoe of silimarina (silibinina) explain antioxidant activity (Braking peroxide oxidation of lipids), stimulation of protein synthesis, the normalization of the exchange phospholipids.

     Beans and capsules are inside, not liquid, a small amount of liquid.

     To treat severe liver failure appointed first legalon-140-1 capsule three times a day, then one capsule two times a day. In less severe cases, and for maintenance therapy designate legalon-70-1 - 2 pills three times a day, further to 1 pills 3 times a day. In severe cases, appoint legalon-70 from 3 2 pills twice a day.

     Suspension appointed at the beginning of treatment and in severe cases, four times a day for one dimensional spoon (10 ml, containing 100 mg silimarina); For maintenance therapy for 1-dimensional spoon 2 times a day (about 200 mg silimarina). Children in severe cases, appoint one measuring spoon three times a day, then to 1 / 2 dimensional spoons 3 times a day.

     The drug is usually well; In some cases there poslablyayuschee effect.

     Method of issuance : Bean legalon-70 to 20; 100 and 400 pills in the package; Legalon-140-20 and 100 capsules in the package; Legalon- suspension on the 450 ml pack.

     Recently developed product silibinina- digidrosuktsinata sodium salt (Legalon FORCES; Legalon SIL) for intravenous infusions. The drug is proposed for use with toxic liver damage caused by poisonous mushrooms Amanita phalloides.

Materials allowed to copy only with the active hyperlink to the handbook of medicines