Ketanserin (ketanserinum)

KETANSERIN (Ketanserinum) *. 3-[2-[4 - (para-Ftorbenzoil) piperidinil] ethyl] -2, 4 (1 H, ZN) - hinazolindion.
     Synonyms: Sufroksal, Serefrex, Sufrexal, Sufroxal.
     Issued in the form tartrata.
     The white or slightly yellow powder.
     Is specific antagonist 5-HT 2 receptor; Moreover, having a moderate-adrenoblokiruyuschee effect.
     Ketanserin blocking serotonin different effects, particularly its effect on muscle spazmogennoe vessels and bronchi effect on the aggregation of platelets.
     With regard to the impact of TB blocker at the 5-HT 2 (S 2) - gistaminovye and a 1-adrenergicheskie receptors product is expanding blood vessels and has antigipertenzivnoe effect.
     Ketanserin used in the treatment of hypertension, for kupirovaniya PNDS crises, as well as violations of peripheral blood (peremezhayuschayasya limp, the disease Reyna, etc.). Assign also in the brain (Peripheral physiotherapists, gemorroidalnom thrombosis, etc.).
     In severe crises impose PNDS 10 mg intramuscularly (2 ml of 0.5% solution) or intravenous dose of 10 to 30 mg (2 to 6 ml at speeds of 5 mg / min).
     After an introduction (bolyusnogo) a dose intravenous infusions of 2 to 6 mg / h. Inside with hypertensive disease and peripheral vascular cramps appoint 20-40 mg 2 times a day (during the meal). Those older appoint 20 mg 2 times a day.
     There is evidence ketanserina application in the integrated treatment of chronic bronchitis (injected intravenously at 10 mg / day for 7 days, then appointed interior to 20 mg / day) '.
     In applying ketanserina should consider cutting hypotension with parenteral introduction; The patient in this case should be in the situation lying down.
     The product contraindications: pregnancy and breast feeding.
     Method of production: tablets of 20 and 40 mg; 0.5% solution in ampoule of 2 and 10 mL (10 or 50 mg).
     Storage: B. list at room temperature.

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