POTASSIUM PERHLORAT (Kalii perchloridum).

     Synonyms : Chlorigene (C), Kalium perchloricum.

     The white crystalline substance and odourless. Little is soluble in water, alcohol in nerastvorim.

     Is antitireoidnym (tireostaticheskim) substances. The mechanism of the drug is related to the braking ability of thyroid iodine to accumulate, leading to oppression tiroksina education.

     Applied mostly in the form of light and medium-toxic goiter.

     Assign to the food inside. Dose and duration of treatment set individually depending on the condition of the patient, severity of disease, treatment, endurance drug.

     The therapeutic dose is 0,5-1 grams a day (in the 2-4 receiving). Higher doses should not be applied. The overall average length of treatment in one year.

     When the drug may relapse.

     To prepare for the operation of the thyroid gland apply potassium perchlorate is impractical because of antitireoidnogo action for a long time; Moreover, the increased risk of bleeding gland.

     Potassium perchlorate treatment to be carried out under the close supervision of a physician.

     In applying the drug may thrombocytopenia, radiation, agranulotsitoz, aplastic anaemia, diarrhoeal phenomenon, disruption of the liver, the heat zobogenny effects and other side effects. In the treatment study to weekly blood.

     The use of the drug potassium iodine after perchlorate may exacerbate thyrotoxicosis.

     The drug is contraindicated in pregnancy, stomach ulcers and gastrointestinal cancers, blood diseases system.

     Product : powder.

     Potassium perchlorate used in conjunction with potassium iodide (see) for the prevention ray thyroid lesions.

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