Izotretinoin (isotretinoine)


IZOTRETINOIN (Isotretinoine) *. 13, cis-Retinoevaya acid.
     Synonyms : Roakkutan, Roaccutan, Accutane.
     Refers to a group retinoidov. Close on the structure of retinol and etretinatu (tigazonu).
     Has protivoseboreynoe operation and applied for the treatment of severe acne skin (non-treatment by other means).
     Assign inwards in the form of capsules from the 0.5 mg / kg per day. After about four weeks to clarify the dose, depending on the effectiveness and acceptability of products, in the range of 0.1 to 1, 0 mg per 1 kg of body weight per day, not exceeding 2 mg / kg.
     The course of treatment lasts for up to 16 weeks.
     Capsule take food with a small dose of 1 times a day, with a few large receptions.
     If necessary, repeat treatments make breaks duration of at least 8 weeks.
     Possible complications and contraindications measures predostorozhsnosti see Etretinat (tigazon).
     Izotretinoin (roakkutan) also teratogenic effects and contraindications women of childbearing age.
     Product : capsules containing 2, 5; 5; 10 or 20 mg izotretinoina.

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