Imehin (imechinum)
IMEHIN (Imechinum). 2, 2, 6, 6-Tetrametilhinuklidina yodmetilat.
The white crystalline powder bitter taste. The easily soluble in water and alcohol; PH 1% aqueous 5, 5-7, 0. Sterile Solution to 100 C for 30 minutes.
On chemical structure is imehin Quaternary temehin derivative products (see). Both are ganglioblokiruyuschimi drugs, but differed imehin that has caused short-term effect and the effect of anti-hypertensive easily manage with appropriate dosing. In that regard, he far more convenient for controlled hypotension and anesthesiological practice than dlitelnodeystvuyuschie ganglioblokatory such as benzogeksony and pentamin.
Compared with applicable for the same purpose foreign drug arfonadom (A rf of nad) imehin less toxic and less long-term effect. Imehin can also be used for cupping PNDS crises and swelling light and the brain.
Enter imehin intravenously.
To run hypotension using drip a 0.01% solution (1 : 10,000); For this to throw 1 ml 1% solution of 100 ml isotonic sodium chloride solution, or 5% glucose solution; Impose a speed of 90-120 drops per minute.
Upon reaching the required effect reduces the number drops to 30 to 50 minutes. With insufficient anti-hypertensive effect of increasing concentration of the solution imehina to 1:5000.
The drug can be administered as a single dose or explored in the 5-7 - 10 mg (0.5-0.7-1 ml 1% solution) in the 5-7 - 10 ml isotonic sodium chloride solution, or 5% glucose solution. Enter slowly once or explored by 2 to 3 ml of 3-and 4-minute intervals. The duration of anti-hypertensive action is 4-20 min.
You can also start with a single 5 - 10 ml of 0.1% solution, and then go to a drip.
Following the introduction of the solution imehina arterial pressure is usually refunded through April 15 min.
Adverse events and contraindications are the same as for the entire group ganglioblokiruyuschih drugs.
In ftorotanovom anaesthesia and use of anti-hypertensive tubokurarina imehina could be stronger.
Product : 1% solution in ampoules of 1 and 2 ml.
Storage : List B. In the dark spot.
|
||
Materials allowed to copy only with the active hyperlink to the handbook of medicines
|
||
