IBUPROFEN (Ibuprofenum). d, 1-2 - (4-Izobutilfenil) - propionic acid.

     Synonyms : Advil, Bolinet lingval, Bonifen, Bren, Brunifen, Brufen, Buran, Children's Motrin, Deep Rilif, Dolgit, Ibupron, Ibusan, Ibutad, Ibuton, Ipren, Markofen, MIG 200, Motrin, Nurofen, Profen, Profinal, Reumafen, Solpafleks, Advil, Algofen, Anflagen, Artofen, Artril, Bonifen, Bren, Brufanic, Brufen, Bufigen, Burana, Children's Motrin, Deef Relief, Dolgit, Ebufac, Iborufen, Ibumetin, Ibuprofen, Ibupron, Ibusan, Ibutad, Ibutop, Inflam, Ipren, Lamidon, Marcofen, MIG 200, Mortifen, Motrin, Napacetin, Nobfen, Nuprin, Norofen, Paxofen, Profen, Profinal, Rebugen, Relcofen, Reumafen, Ruprin, Seclodin, Sendafen, Solpaflex and others.

     White or almost white crystalline powder. Almost nerastvorim water, easily soluble in organic solvents.

     The drug is a modern non-steroid anti-drugs. Has antiinflammatory, and analgeticheskoy moderate analgesic activity.

     In the framework of the derivatives significant role played by his inhibition effect on the biosynthesis of prostaglandines.

     While the catalytic impact of derivatives on education endogenous interferon (see Interferony) and its ability to provide ummunomodulating and improve the rate of non-resistance.

     Ibuprofen with rheumatoid arthritis has a stronger effect in the early stages of the inflammatory process without abrupt changes in the joints. By virtue of it somewhat less ortofenu, indometacin, but better postponed.

     Applied for the treatment of rheumatoid arthritis, osteoarthritis deforming, ankylosing spondylitis, and the various forms of joint and vnesustavnyh Rheumatoid diseases, as well as pain in certain inflammatory lesions of peripheral nervous system.

     Assign inwards in the form of tablets to 0.2 g 3 - 4 times a day. To achieve rapid effect dose can be increased to 0.4 g three times a day. Upon reaching the therapeutic effect to reduce the daily dose of 0.6 - 0.8 g.

     The first recommended daily dose in the morning before eating (for a quick intake), squeezed tea, and the remaining doses for a period of days after food (for a more gradual intake).

     The drug is usually well without causing stomach irritation of mucous membrane, which is seen as its main advantage over musk. In some cases is possible, however, flatulence, nausea, vomiting, flatulence, and allergic skin reactions. When expressed adverse events reduce the dose or stop receiving the drug.

     Ibuprofen is contraindicated in acute ulcer and acute gastric ulcer and duodenal ulcer, ulcerative colitis, high sensitivity to individual drugs, as well as the visual nerve diseases.

     Caution should be observed in the appointment of a drug persons who had in the past gastric ulcer disease and gastrointestinal cancer, and gastritis, enteritis, colitis, chronic hepatitis, liver cirrhosis.

     Product : pills to 0.2 g-coated pinks, in a package of 30 pieces.

     Storage : List B. In dry, the dark spot.

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