GEKSAMETILENTETRAMIN (Hexamethylentetraminum).

     Synonyms : Urotropin, Aminoform, Cystamine, Cystogen, Formamin, Hexamethylentetramin, Hexamina, Methenamine, Metramine, Urisol, Urotropinum and others.

     Clear crystals or a white crystalline powder burning and sweet, then bitter taste, and odourless. The easily soluble in water (1:1, 5) and alcohol (1:10). When heated surface is not melting. Solid pale flames.

     Aqueous solutions are alkaline reaction (40% solution of pH 7, 8, 8, 2). For intravenous solution are filled.

     Getting geksametilentetramina was the first experience (in 1899), a medicinal substance, which is now called prolekarstvom (see Fenilsalitsilat). With the collapse geksametilentetramina in the body (the acid) released formaldehyde, a withdrawal from urine with antiseptic properties.

     Hexamine applied as a means of antiseptics in infectious processes in the urinary tract (cystitis, pielity).

     In response alkaline urine off formaldehyde is not the case and no therapeutic effect. In these cases designate substances HPC reaction in the urine acidic side (see Ammonium chloride).

     To prevent splitting geksametilentetramina in the stomach, he was appointed shock. If necessary, enter geksametilentetramina solution intravenously.

     Testimony to use geksametilentetramina also cholecystites and holangity, allergic skin diseases (urticaria, erythema polymorph, etc.), eye disease (iridotsiklity, keratitis, etc.). Drug use also with meningitis, encephalitis, Arachnoiditis.

     Now, because of more efficient means Hexamine is widely used.

     Assign inside tablets and solutions for adults 0.5 to 1, 0 g admission, children under 0.1 - 0.5 g; Take several times a day. In the vein type of 5-40% 10 ml solution.

     Hexamine can cause irritation parenhimy kidneys, and in some cases help to spread the painful process pielite. When signs of irritation receiving kidney drug stop.

     Method of issuance : powder; Tablets of 0.25 and 0.5 g; 40% solution in ampoules of 5 and 10 ml.

     Storage : a well ukuporennoy packaging; Solutions - with a temperature of no higher than 20 + C.

     Hexamine is part of the combined pill <Kaltseks Urobesal> and <> (see Fenilsalitsilat). Previously issued pills <Urosal> containing 0.3 grams of geksametilentetramina and fenilsalitsilata are excluded from the range of medicines.

     Pills <> (Kaltseks Tabulettae <Calcex>). Pills white solenogorkie taste. The easily soluble in water. Contain 0.5 grams of salt integrated geksametilentetramina and calcium chloride. Applied to 1 - 2 - 3 tablets 4 times a day when diseases. Earlier drug was relatively widespread use. Currently, due to the low efficiency of the drug almost lost value, but not yet removed from the range of medicines.

     Product : pills in glass probirkak (10 pieces).

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