GALOPERIDOL (Haloperidolum). 4 - (steam Hlorfenil) - 1 [3'- (para-ftorbenzoil) - propyl] - piperidinol-4 or 4-[4 - (para-chlorophenyl) -4 - oksipiperidino] -4 '- ftorbutirofenon.

     Synonyms : Galofen, Aloperidin, Haldol, Halidol, Haloperidin, Haloperin, Halophen, Haloperidol, Halopidol, Serenace, Seranase and others.

     Haloperidol is one of the most active contemporary Neuroleptics. It has a sedative effect, potentsiruet of sleeping pills, drugs and analgetikov. Central Lock-noradrenergicheskie and a particularly strong central dofaminergicheskie receptors; Central and peripheral antiholinergicheskogo do not have. Relatively frequently extrapiramidale violations. Has strong protivorvotnoe effect.

     Haloperidol is an effective way to bring all sorts of edema, especially in the state of mania, a severe delirium. Often effective in patients resistant to other neurotic substances. Unlike aminazina leaves patients weak and apathy, in contrast, has activating effect.

     Applied with schizophrenic psychosis, delusional state, paranoidnyh raving state, with azhitirovannyh depression, oligofrenicheskih, involyutsionnyh, epileptiformnyh, alcoholic psychosis and other diseases involving hallucinations, psychomotor proceedings.

     In the case of alcohol deliriya with visual hallucinations by haloperidol is rapidly disappearing motorized comfort and hallucinations.

     Haloperidol may be used in combination with drugs, analgesics and other neurotropic medications in preparation for the operation. There is evidence of the effectiveness of a drug for pain palpitations, triggering nausea and vomiting in acute coronary insufficiency (often with analgesics).

     As protivorvotnoe funds can be used in different origins vomiting.

     In small doses used in the neurotic and reactive state.

     Assign inside (to food), or intramuscularly.

     Initial daily intake in the absence of an express 0.0015 - 0.003 g (1, 5, 3 mg) inward, and in patients resistant to neuroleptic drugs, 0.0045 g (4, 5 mg). The daily dose divided into three receiving and taking tablets or drops half an hour after a meal. Daily dose increase of 0.5 to 2 mg (resistant cases of 2 to 4 mg) to obtain therapeutic effect. Therapeutic daily intake is usually 10 to 15 mg / day, and chronic forms of schizophrenia-20-40 mg (50-60 mg). Duration of treatment 2 -3 months. Older dose slowly. Supported doses ranging from 0.5 to 5 mg a day.

     Children under the age of five years are 1 / 4 of 6 to 15 1 / 2 adult dose.

     To initiate edema psychomotor designate intramuscularly in the first days of February 5 mg (0.4 - 0.5 ml of 1% solution) 2 - 3 times daily. On reaching effect on the admission of drug moving inside.

     As protivorvotnoe haloperidol appointed interior adults to 0,0015 0,002 g (1, 5, 2 mg); As uspokaivayuschee- to 0.0005 g (0.5 mg).

     The most significant complications in the use of haloperidol is extrapiramidale disorder in parkinsonizma, akatizii, distonicheskih events. For edema these phenomena designate antiholinergicheskie ANTIPARKINSONISM means (tsiklodol, tropatsin et al). Early treatment can be observed haloperidol stroke motor excitation and apnoea reduce various muscle groups (front muscles, torso muscles). These phenomena can be deflationary intramuscular introduction aminazina (0.05 g) or caffeine. There may be the phenomenon of anxiety and fear. When possible overdose insomnia. In the early days of treatment there may be a slight reduction in AD. In the process of treating skin reactions are possible (toksikodermiya bladdery type) and increased skin sensitivity to sunlight (photosensitization).

     When taken drugs inside (especially PCP) can be nausea and vomiting.

     The drug is not suitable for central nervous system diseases with the pyramid and ekstrapiramidnoy symptoms, and hysteria. Caution must be exercised in cardiovascular disease events with decompensation, violations conductivity cardiac muscles, severe kidney disease. There are reports of possible symptoms nesaharnogo diabetes, acute glaucoma, trends (in long-term care) to develop limfomonotsitoza.

     There is a need to be cautious about the use of haloperidol combined with drugs and analgesics (especially opiates), a dramatic increase in their actions.

     Method of issuance : pills to 0.0015 and 0.005 g - (1, 5 and 5 mg) in a package of 50 pieces; 0.2% solution for the reception inside in vials of 10 ml (10 drops contain 1 mg haloperidol); 0.5% solution in ampoules to 1 ml pack of five vials.

     Storage : B. list at room temperature.

     Abroad issued prolonged form for parenteral haloperidol (intramuscular) application - haloperidol decanoate. One injection provides curative effect for about four weeks.

     R p. : Tab. H aloperidoli 0.0015 N. 50

     D.S. At one tablet three times a day

     R p. : Sol. Haloperidoli 1 ml 0.5%

     D.t.d. N. 5 in ampull.

     S. At 0.4 to 1 ml intramuscularly

     R p. : Sol. H aloperidoli 0.2 ml 10%

     D.S inside. In 10 drops three times a day.

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