Gemodez (haemodesum)
GEMODEZ (Haemodesum).
Water saline solution containing 6% nizkomolekulyarnogo polyvinylpyrrolidone (relative molecular mass 12600 2700) and sodium ions, potassium, calcium, magnesium, chlorine.
Polivinilpirrolidon (PVP) is a polymer compounds; Well soluble in water.
Gemodez-transparent liquid yellow; The relative viscosity of 1, 5, 2, 1; PH 5, 2, 7, 0.
Applied to the body's detoxification of toxic forms of diarrhoea (dysentery, neuralgia, salmonelezy etc.), burn disease in the phase of intoxication post intoxication, infectious diseases, pregnant toxicosis and other pathological processes involving intoxication.
Drugs similar gemodezu, produced abroad under the title : Neocompensan, Re ristan N et al.
Mechanism of action due to the ability gemodeza nizkomolekulyarnogo polyvinylpyrrolidone bind toxins circulating in the blood, and quickly pull them from the body.
The drug quickly displayed kidneys (80% for 4 h), and partly through the intestines.
It increases renal blood flow increases klubochkovuyu filtering and increases Diurez.
Enter gemodez intravenous drip at speeds of 40 to 80 drops per minute. If not, intravenous subcutaneous acceptable, but the effect it is less pronounced.
Solution to the introduction of fuel to + 35 ; + 36 'C. Adults once imposed 300-500 ml; For children 5 to 10 ml / kg.
Repeated infusions produced within 12 hours or more after the end of the previous Infusion.
The number of introductions, and the total number of input gemodeza depend on the nature and a pathological process. In diarrhoeal diseases and intoxication usually enough 1 - 2 infusion. When Burn disease in the phase of intoxication (1-5-day sickness) in the phase of intoxication and acute radiation syndrome produce 1 - 2 injection, and hemolytic disease of the newborn and toxaemia is from 2 to 8 infusions (a day or two times a day).
Gemodez can give a good detoxification effect in sepsis, but the possible reduction in blood pressure, it is necessary to carefully monitor the patient.
In the slow introduction gemodez usually does not cause complications. The introduction of high speed can cause reduced blood pressure, tachycardia, difficulty in breathing and require a sosudosuzhivayuschih and heart of calcium chloride.
The drug is contraindicated in bronchial asthma, acute nephritis, a brain haemorrhage.
Product : in the hermetically ukuporennyh glass receptacles for the blood of 100; 200, and 400 ml.
Storage : at a temperature of 0 to + 20 C. Freezing does not affect the quality of the preparation.
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