Gramicidin (gramicidinum)


GRAMITSIDIN (Gramicidinum).
     Gramicidin (gramicidin A) is the antibiotic that has a bacteriostatic effect on microbicides and streptococci, stafilokokki, pnevmokokki, agents anaerobic infections and other microorganisms.
     Produtsiruetsya sporovoy sticks Bacillus brevis var. G.-B.
     Issued in ampoule in a 2% solution of sterile alcohol. A transparent liquid from light yellow to yellow. Since water is a opalestsiruyuschie solutions, heavily eye when shaking.
     Gramicidin apply only locally. Introduction solutions in the veins is not allowed (subject to haemolysed and flebita).
     For manufacturing practices used in aqueous solution gramitsidina X, the contents of the syringe and pull ampoule razvodyat 100-200 times the usual sterile or distilled water. Water gramitsidina solution can be used within 3 days after cooking. To manufacture therapeutic solution original 2% solution gramitsidina razvodyat 100 times 70% alcohol. To manufacture fat source solution gramitsidina 2% solution razvodyat fat (castor oil, fish oil, ml, etc.) 25-30 times. Curative alcohol solution and the fat solution can be stored a long time. Shelf life alcohol solution gramitsidina in sealed ampoule not restricted.
     Aqueous solutions gramitsidina used for flushing, irrigation dressing, baking, etc. the treatment treat wounds, bedsores, ulcers, osteomielita, injuries to joints, empiem, complications appenditsitov, phlegmon, carbuncles, furunkulov etc., to wash and mouthwashes in inflammatory diseases ear, throat.
     For treatment of wounds, burns, etc. gramitsidinovaya paste can be applied (see). Due to the presence gramitsidina expressed spermatotsidnogo actions paste used as contraception.
     In piodermii and treat skin diseases are alcohol solutions gramitsidina: lubricating skin 2 to 3 times a day.
     Storage: in sealed ampoule in a cool, sheltered from the world scene.
     Rp. : Sol. Gramicidini spirituosae 2% in 5 ml ampule.
     D.S. Razvesti in 500 ml of sterile distillirovan by water. For exterior use
     Gramitsidinovaya paste (Gramicidini Pasta). Implemented as a local contraceptive method and as a local antibacterial tool in the treatment of burns and wounds.
     Composition pasta: 2% alcohol solution gramitsidina 9, 89%, 40% solution dairy acid 0.51%, emulsifier 15% distilled water in 1974, 6%.
     Issued in wet or banks of 30 g.
     Cause thin layer on the skin surface, cover marlevoy napkins. Bands change after 2 to 4 days. As contraceptive means to enter the vagina special syringe 5 - 6 g drug.
     Storage: in a cool, sheltered from the world scene.
     Tablets gramitsidina S (Tabulettae Gramicidini). Tablets yellow sweet taste, contain 1, 5 mg (ED 1500) gramitsidina S.
     Designed for field use (zaschechnogo) (rassasyvayutsya slowly in the mouth) with acute faringitah, aftoznyh defeat mucosa and mouth disease, gingivitis, angina.
     Apply 2 tablets (one after the other for 20 - 30 min) four times a day. Keep pills in the mouth, not proglatyvaya to complete resorption. In the course of 10-20 pills.
     Form release: tablets in glass vials or tubes 10-20 pieces.
     Storage: in a dry, cool, sheltered from the world scene.

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