GEMFIBROZIL (Gemfibrozil) *. 5 - (2 5-Dimetilfenoksi) -2, 2-dimetilpentanoevaya acid.

      Synonyms : Gevilon, Dopur, Gevilon, Hipolixan, Lipigem, Lipozid, Lopid, Normolip and others.

      Received as a result of derivative klofibrata, with less toxicity. Gemfibrozil has been of low and yet highly lipid means that limits LPONP content in the blood of patients with gipertriglitseridemiey not reagiruyushih treatment lipid diet and other means. In addition, it increases the concentration LPVP.

      Gemfibrozil quickly and almost completely absorbed by ingestion. Peak concentrations in the blood is 1 to 2 h after administration. Provided mainly in the form of kidney glyukuronidov.

      Assign an adult to 0.3 - 0.45 g 2 times a day (30 minutes before breakfast and dinner). The full effect of treatment developed by 3 - 4 weeks. Assign gipertriglitseridemiey in patients with clinical resistance to diet and other lipid vehicles. In giperhilomikronemii due to family lipoproteinlipazy deficit, weak medicine.

      Gemfibrozil is usually well. Chance of illness disorders (abdominal pain, nausea, diarrhoea.) . In rare cases, a small anemia, radiation. Like klofibratu (but fewer) can assist in the biliary stones.

      Contraindications patients with gallbladder disease. The drug is not appointed pregnant and children.

      Potentsiruet of anti.

      Method of issuance : capsules to 0.3 g (300 mg); Pill-coated (white), to 0.45 g.

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