Furazolidon (furazolidonum)
FURAZOLIDON (Furazolidonum).
N - (5-Nitro-2- furfuriliden) - 3-aminooksazolidon-2.
Synonyms: Diafurone, Furazolidone, Furoxon, Neftin, Neocolene, Nifulidone, Optazol, Rivopen-O, Trichofuron, Tricofurin, Trifurox and e p.
The yellow or greenish-yellow powder, odourless, slabogorky taste. Almost nerastvorim in water, very little of alcohol.
Effective against gram and gram bacteria. In addition, a protivotrihomonadnoy activity. The product is also effective when coli. Of pathogens intestinal infections most sensitive to furazolidonu agents dysentery, typhoid and paratyphoid.
Compared with furatsilinom and furadoninom, furazolidon more active against gram bacteria, it is also less toxic. Relatively little impact on the eight agents and anaerobic infections.
One of the positive features furazolidona is that the resistance to the microorganisms growing slowly. It is effective against a number of bacteria resistant to antibiotics and sulfanilamidam.
Inside furazolidon appointed with dysentery, paratife, nutritional diseases. Provide for 0.1 - 0.15 g (adults) four times a day (after the meal) for 5 to 10 days. Doses for children under diminish with age. The length of treatment depends on the nature and severity of the infection. You can also designate the drug doses in the same cycles for 3-6 days every 3-4 days. Not to take the drug for more than 10 days.
In trihomonadnyh obesity, drug use combined: the interior of 0.1 g 3 - 4 times a day during the three days; While the vagina impose 5 to 6 grams of powder containing furazolidon with milk sugar in 1:400, 1:500, but in the rectum-candles containing at 0,004-0,005 grams (4-5 mg) drugs. Repeat procedure every day during 7-14 days. In trihomonadnyh genitals take furazolidon inside of 0.1 g four times a day during the three days.
When E. assign adults to 0.1 grams four times a day, the children at the rate of 10 mg / kg / day, the distribution of the daily dose of 3-4 at the reception.
Higher doses for adults: an inside 0.2 g daily 0.8 g.
Solution furazolidona (1:25 000) can be used for the treatment of burns and traumatic infections in the local irrigation and vlazhnovysyhayuschih dressing.
When you receive furazolidona often appear on the inside of nausea, vomiting, decreased appetite. In some cases vozmozhy allergic reactions (exanthema and enantemy). To reduce adverse reactions to more my furazolidon more liquid and, if necessary, reduce the dose, appoint protivogistaminnye drugs, calcium chloride, vitamins Group B. expressed adverse drug events receiving end.
Contraindications are the same as for furatsilina.
Please note that furazolidon is monoaminoksidazy inhibitor; In its application must be respected to the same precautions as when using monoaminoksidazy inhibitors.
Furazolidon has the ability to sensitize the body to the action of alcohol and used for the treatment of alcoholism with insufficient funds or other available contraindications to their use.
After receiving furazolidona (within 10 to 12 days) usually produced uslovnoreflektornaya negative reaction to drink alcohol. Admission alcohol amidst furazolidona is feeling heat in the face and neck, burning sensations in the body, gravity in the back field, in addition, bewitching pulse, declining AD.
Form release: pills to 0.05 grams in a package of 20 pieces.
Storage: List B. In sheltered from the world scene.
For applications in infectious diseases gastrointestinal tract in children produced granules furazolidona (Granulae Furazolidoni pro infantibus).
Granules yellow or greenish-yellow with weak specific odor.
To make the contents of the vial suspension svezheprokipyachennoy dissolve in warm water (to the label on vial for a 100 ml).
Assign to 4 times a day after eating children up to 1 year in 4 ml dose-time, 1 - 2 years 4 - 5 ml, 3 to 4 years to 6 - 7 ml, 5, 6, 7 years old, 5 - 8 5 ml. Before the use of suspensions vzbaltyvayut.
Form release: granules 50 grams glass banks with a capacity of 150 ml to annex dimensional cup.
Storage: List B. In a dry, sheltered from the world scene.
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Materials allowed to copy only with the active hyperlink to the handbook of medicines
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