FLUTAMID (Flutamide). 4'- Nitro-3'- triftormetil- izobutiranilid. Synonyms: Flutsinom, Flyutsinom, Cebatrol, Drogenil, Euflex, Eulexin, Flucinom, Fugerel, Fulforel, Hibitron, Norex and others.

     The product blocks linking androgenov (HSBG) cell receptors and prevent the occurrence of the biological effects of androgenov androgenochuvstvitelnyh bodies, including the prostate gland tumor cells.

     Apply flutamid (niftolid) mainly for the palliative treatment of advanced prostate gland cancer.

     Assign inwards in the form of tablets (to 0.25 g) on one tablet three times a day. The preparation for admission into the rapidly absorbed. The half was 5 to 6 hours Most kidney appears in the form of metabolites.

     Treatment for a long time (depending on the period of the disease).

     The product is usually well tolerated by. In a lengthy application development possible ginekomastii, pain in the milk glands. In some cases, perhaps a slight increase in the concentration metgemoglobina, which is transitory in nature.

     In the treatment should periodically examine the function of liver. It should be careful in appointing a drug persons suffering from cardiovascular diseases.

     The product is used for differential diagnosis gipogonadizma men. To this end appoint 10 mg / kg / day in 3 admission for three days to study excretion gonadotropinov.

     Application flutamida counter with heavy diseases of liver, kidney, thyroid gland.

     Form release: pills (light yellow) to 0.25 g.

     Storage: at room temperature.

     Close on the structure and actions to niftolidu, is a non-steroid drug antiandrogenom nilutamid. (Nilutamide; A synonym anandron-n and ndron) - 5 5-Dimethyl [nitro-3- 4 - (trifluoromethyl) phenyl] -2, 4-imidazolidindion.

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