FLUKONAZOL (Fluconazole). 2 - (2, 4-Diftorfenil) -1, 3-bis (1 H-1, 2, 4-triazol-1- mud) -2-propanol.

     Synonyms: medicine, Diflucan.

     Anti-drug, a new chemical group derived triazolya; 2 contains fluorine atom.

     Provides expressed anti effect; Specific synthesis inhibited fungal easily.

     Quickly absorbed in the employment inside. Lengthy stored in blood plasma. Report the mainly kidneys (80%).

     Apply in various fungal infection: when kriptokokkoze, including kriptokokkovy meningitis; While systemic candidiasis, candidiasis mucous membranes, vaginal candidiasis; To prevent fungal infections in patients with malignant tumors in the treatment of tsitostatikami or a radiation therapy; In organ transplants, and in other cases, when depressed immunity and the danger development funghus infection.

     Assign fluconazole inside and intravenously.

     For intravenous drug produced in a 0.2% solution and isotonic sodium chloride solution for reception inside the capsules 50; 100; 150, and 200 mg in a syrup containing 5 mg in 1 mL (0.5%) .

     Daily dose of both methods of the same. With regard to the long half, just take one product every day. Conventional treatment doses ranging from 200 to 400 mg per day, with candidiasis mucous membranes-50-100 mg / day; With 150 mg vaginal candidiasis. The length of treatment depends on the nature of the disease and the effectiveness of drugs (from July 14 to 30 days).

     Usually drug is well tolerated by. Possible diarrhea, bloating, skin rash.

     The product should not be appointed during pregnancy and breast feeding, and children under 16 years of age.

     Fluconazole increases of antikoagulyantov, oral gipoglikemicheskih funds gidrohlortiazida, difenina. In combination with rifampicin, flukonazola shortened half-time, there was a need for some increase in dose.

     Method of issuance: capsules, syrup, intravenous solution.

     Storage. : List B.

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