FLAVINAT (Flavinatum).

     R-1 (Riboflavin-5 ') - 2-R (Adenosine 5') - diphosphate ethylenediaminetetraacetate salt.

     Yellow-orange crystalline powder bitter taste. Gigroskopichen.

     Light and fragile at elevated temperature. Easy soluble in water, virtually nerastvorim in alcohol.

     Flavinat (flavinadeninnukleotid; FAD) is kofermentom, which is formed in the body of riboflavin (if fosforilirovanii flavokinazy under the influence of the mucosal skin ulcers, and the biotransformation, kataliziruemoy pirofosforilazoy with AMF). Flavinadeninnukleotid, making contact with a specific protein, is the enzymes involved in okislitelnovosstanovitelnyh processes, the exchange of amino acids, lipids and carbohydrates (See Fosfaden).

     For use as a medicine ethylenediaminetetraacetate salt flavinadeninnukleotida obtained by synthetic and named "Flavinat." This freeze dry porous mass of yellow-orange; Fluid to light and exposure to high temperatures; Rastvorima water; PH of the solution (0,002 grams in 1 ml of water), 6-3, 7, 5.

     Abroad, a similar product produced under the title: Adeflavin, Bisflavin, Flavinin, Flavitan and others.

     Apply flavinat in sensing and beri In February, especially if there is no effect of riboflavin inside. Unlike Pharmacological flavinat can enter parenteral transmission, it is effective in violation of riboflavin intake in the gastrointestinal tract. Also effective in violation fosforilirovaniya riboflavin.

     Flavinat used in the treatment of Dystrophic changes in the eye retina, glaucoma, chronic liver, pancreas, bowel, and some skin diseases (pink and black young people, etc.) as well as disease-related deficits glyukozo6- fosfatdegidrogenazy etc.

     Enter drug intramuscularly (slow); Dystrophic diseases in the eye, under the conjunctiva eyeball.

     Intramuscularly usually imposed on 0,002 adults g (2 mg), 1 to 3 times a day. Children enter for 0,001 - 0,002 grams per day. The course of treatment lasts from 5 to 30 days and more (up to 40). If necessary, repeat treatments at 6 months.

     In the case of long-term therapy flavinat imposed on 0,001 - 0,002 grams 1 time per day.

     To prepare the injection solution flavinata immediately before use. The contents of one ampoule (0,002 grams) dissolve in 2 ml of water for injection.

     In Dystrophic retina of the eye imposed under conjunctiva each eyeball to 0.3 ml 0.2% solution (0.6 mg drug) in a day; Course 10 - 15 injection. Courses can be repeated through 8 - 12 months.

     In komplksnoy glaucoma therapy used intramuscularly to 0,002 g 1 drug once a day every day for 10 days.

     When in the case of drug podkonyunktivalnogo headache, dizziness, long watering stop a drug under the conjunctiva and move on intramuscular injection.

     Form release: flavinat 0,002 g for injection (Flavinatum 0,002 p ro injectionibus) in the ampoule with a capacity of 3 to 5 ml vials in the package complete with water for 5 ampoule nnektsy to 2 ml.

     Storage: in a protected place of light at room temperature.

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