ETIDRONAT sodium (Etidronate sodium).

     Ethylenediaminetetraacetate salt (1-oksietiliden) difosfonovoy acid.

     Synonyms: Ksidifon, Pleostat, Didronel, Pleostat, Xydifonum.

     When you receive inside well absorbed, T? at about 6 h; not being biotransformation, appears kidneys.

     Indications for use mainly the same as for other bifosfonatov (osteoporosis, a disease Pedzheta, giperkaltsiemiya with cancer and other diseases). Apply also oksalatnom type urethrocystitis disease.

     Assign inside and intravenously.

     Normal adult dose inside (morning), 5-7 (20) mg / kg / day in combination with calcium products (0,5-1 g.) and vitamin D (400-800 ED holekaltsiferola or 0,5-1 ug alfakaltsidola ) courses for 1-2 months.

     Intravenous kapelno enter slowly (2 h) in the dose of 7.5 mg / kg (in 250 mL of 0.9% sodium chloride solution) within 3-5 days.

     Possible side effects: metallic taste in the mouth, smell disorders, kidney function violation.

     The product contraindications to gipokaltsiemii, violation of kidney function and pregnancy.

     Method of production: tablets of 0.4 g (N. 14); 20% concentrate for solution for the reception inside in vials of 50, 100 and 250 ml; 5% solution for Infusion.

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