ETOSUKSIMID (Ethosuximidum). 3-Etil-3- metilpirrolidin-2, 5-dione, or a - ethyl-a metilsuktsinimid.

     Synonyms: Asamid, Piknolepsin, Ronton, Suksilep, Etomal, Aethosuximid, Asamid, Ethymal, Etomal, Pemalim, Petinimid, Pyknolepsin, Ronton, Succimal, Suxilep, Zarontin and others.

     Has protivosudorozhnoy activity, reflected, as the trimetina in small forms of epilepsy. Also effective in mioklonicheskih attacks. Several less toxic than Trimethadione.

     Assign inside (taken during the meal). Initial daily dose for children 0,25 g, for older children and adults - 0.25 - 0.5 grams per day with a gradual increase in dose for adults to 0.75 to 1 g / day (3 - 4 admission).

     The product has analgesic effect in troynichnogo nerve neuralgia (see Karbamazepin), but somewhat less effective than Carbamazepine. Assign to 0.25 g dose and gradually increasing doses to 0.5 to 1 g per day. Supporting dose of 0.25 g per day.

     Possible side effects: gastrointestinal disorders, in rare cases, headache, dizziness, skin rashes, photophobia. There may be events VGA. It is the development of neutropenia, agranulotsitoza, albuminurii.

     In the treatment should be performed blood tests and urine.

     Please note that the drug can provoke the emergence of large attacks of epilepsy.

     Ethosuximide permeates through the placenta barrier milk in lactating women. Therefore, pregnant and breast-feeding is not recommended product award.

     Method of issuance: called Suksilep "available in capsules of 0.25 g (in the package for 100 and 150 pieces) and in a solution containing 100 mL of 5 g of drugs, 25 grams of glycerol and 25 ml of a mixture of water and alcohol (in vials of 50 g); 15 drops of solution containing 0.25 g etosuksimida.

     Storage: List B.

Materials allowed to copy only with the active hyperlink to the handbook of medicines