ERGOKALTSIFEROL (Ergocalciferolum).

     VITAMIN D 2 (D Vitaminum 2). Methyl-24-9, 10-sekoholesta-5, 7, 10 (19), 22-tetraen-3-ol.

     C inonimy: Kaltsiferol, Aldevit, Calciferolum, Dekristol, Deltalin, Detamin, Drisdol, Fordetol, Infadin, Ostelin, Ultranol, Vigantol, Viosterol, Vitadol, Vitaplex D Vitasterol and others.

     Apply mainly for the prevention and treatment of rickets.

     To prevent rickets among newborns and infants vitamin D2 assign pregnant women and nursing mothers. At 30-32 th week of pregnancy appoint vitamin D 2 fractional doses for 10 days, for a total of 400000 - 600000 course IU. Nursing mothers appoint 500 IU daily from the earliest days prior to the feeding of the drug in the child. Unwanted children are beginning to drug prevention to 3 weeks of age. The total dose of prevention rate is usually about 300000 IU. Premature children, twins, children in artificial feeding, and poor domestic and climatic conditions are beginning to vitamin D2 2 nd week of life. The total dose at the rate of such cases to 600,000IU.

     As a means of preventive medicine can assign different methods: the "split" method of the child are ezhedneno 500-1000 IU during the first year of life; Using the "vitamin jolting" to give IU 50000 1 times per week for 8 weeks . By "surface" method recommended premature children and children with frequent attendant diseases are 300000 - 400000 IU for 10 to 12 days.

     After treatment with vitamin D for the first two years of life product to appoint the spring and autumn-winter (up to 2 years). In areas with a long and harsh winter supportive prevent rickets spend up to 3 years.

     For treatment of rickets I Unwanted children are daily 10000-15000 IU within 30-45 days. At the rate 500000 600000 IU. In severe expressed give this process a dose of "soft" methods within 10 days.

     In rickets II of the course-designate 600000 800000 IU. In subacute during drug taking within 30 -35 days, with a sharp-10 - 15 days.

     In rickets II-III for the prevention of relapse to appoint a second child treated in the dose of 400,000 IU to be implemented within 10 days.

     In rickets III of appointing a course-800000 1000000 IU. In subacute during rickets is the number entering for 40-60 days, with a sharp-within 10 to 15 days.

     For the treatment of severe acute rickets or related pneumonia can enter vitamin D 2 "hit" method (in the hospital), and give 600000 - 800000 IU for 3 to 6 days.

     When disorder osteoporosis designate a day to 3,000ME of vitamin D 2 in 45 days.

     Apply also in disarray as okoloschitovidnyh iron; In particular, tetanii, bone disease caused by the violation of calcium exchange with some form of tuberculosis, blood, etc. In order to prevent attacks tetanii appointed to one million IU of vitamin per day.

     Ergocalciferol is an effective means of treating brain skin and mucous membranes. Daily dose for adult patients tuberculosis Lupus is usually 100000 IU. Children under the age of 16 suffering from tuberculosis Lupus, appointed in doses of 25,000 to 75,000 IU per day, depending on age. The daily dose divided into two receiving and taking in food. The course of treatment 5 to 6 months.

     The product contraindications with hyper, active forms of pulmonary tuberculosis, gastrointestinal tract infections, stomach ulcer disease and stomach cancer, acute and chronic diseases of the liver and kidneys, hearts organic defeat.

     Using large doses of vitamin can develop phenomenon intoxication (gipervitaminoz D): loss of appetite, nausea, headache, general weakness, irritability, sleep violation, increased body temperature, the appearance in the urine gialinovyh cylinders, protein cells. These events usually take place after an interruption of treatment and dose reduction.

     Typical for gipervitaminoza D are increasing calcium content in the blood and improve the allocation of urine. Chance of calcification of soft tissues, kidneys, lungs, blood vessels. The toxic effect of large doses of vitamin D 2 weakened while receiving vitamin A.

     If signs gipervitaminoza repeal product, severely limit the introduction of calcium in the body.

     Care must be taken to appoint ergokaltsiferola elderly, as well as increasing deposits of calcium in the body, it can contribute to the development of atherosclerosis. In addition, caution is needed in the appointment ergokaltsiferola pregnant aged over 35.

     It should be borne in mind that vitamin D 2 has cumulative properties. The drug should be taken under medical supervision and with a long application to the study of calcium in the blood and urine.

     When treating large dose ergocalciferol to appoint a vitamin A to 10000-15000 IU per day, and askorbinovuyu acid and vitamins Group B.

     Ergocalciferol (vitamin D 2) available in the following dosage forms.

     Beans ergokaltsiferola 500 IU (for prevention).

     Solution ergokaltsiferola in oil to 500 or 1,000 IU capsules (for preventive purposes).

     Solution ergokaltsiferola in oil 0.0625%; 0.125% or 0.5% (E Solutio rgocalciferoli oleosa 0.0625%; Aut% 0,125 0.5%). Contains in 1 ml 25000; 50000 and 200000 IU.

     Apply in preventive and curative purposes. One drop of a 625; 1250 5000 or IU.

     Solution ergokaltsiferola in 0.5% alcohol (Solutio Ergocalciferoli spirituosa 0.5%). Contains 1 ml 200000 IU.

     Apply for treatment and prevention purposes. One drop contains about 4,000 IU.

     Drugs vitamin D 2 in the store, excluding effects of light and air, inaktiviruyuschih them; Oxygen air pollutant vitamin D, and the light makes it a poison toksisterin. Vitamin D and its products continue to caution (list B). Beans ergokaltsiferola store in a dry, sheltered from the world scene. Mix in oil-filled up in the well ukuporennyh bottle orange glass in sheltered from the world scene with a temperature of not more than 10 'C.

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