Emetina hydrochloride (emetini hydrochloridum)
EMETINA HYDROCHLORIDE (Emetini hydrochloridum)
Synonym: Emetinum hydrochloridum. Digidrohlorid emetina alkaloid contained in ipecacuanha root. The white crystalline powder, odourless, bitter taste, legkorastvorim in water (1:8) and alcohol. Aqueous solutions to sterilize + Sv 100 for 30 minutes; 1% solution pH 4, 5, 6, 0. Apply with amoebic dysentery. Enter under the skin or muscle adults and 1, 5 mL of 1% solution 2 times a day. Higher doses for adults: single 0.05 g (1 ml of 5% solution), the daily 0.1 g (10 mL 1% solution).
Doses for children
Age Child Daily dose, g
From 6 months to one goal .. . ... 0,005>> 1 year to 2 years ... ... 0.01>> 3 to 5 years ... 0.02>> 6 to 9>> ............ 0.03>> 10 - 15>> ............ 0.04
These doses should not exceed. Children under 6 months. emetine not appointed. Duration of treatment cycles of 4 to 6 days, a maximum of 7 to 8 days. When the chair is designed or poluoformlenny form, the introduction emetina stop and move on to other protivoamebnye drugs. Dose emetina of treatment should not exceed 0.01 g (10 mg) hr kg body weight patient; In the vast majority of cases dostatochnyznachitelno smaller dosage. Typically, emetine appoint tolkopri acute intestinal manifestations. Because cumulative properties emetina repeat cycle of treatment with this drug can be no earlier than July 10 sutposle end of the previous cycle. In the first acute proyavleninh amoebic dysentery usually dostatochno1-2 cycles of treatment emetinom. In protracted number of cycles increases to 3 - 4, at the same time be nominated antibiotics and other antimicrobial drugs. There are performance emetina hydrochloride in the treatment of herpes zoster. Enter intramuscularly to 2 mL 1% solution 2 times a day (morning and evening). In an early start treatment quickly (within two days) cease pain and plasma.
Injections emetina generally well tolerated. In overdose might weakness, nausea, vomiting, muscle pain in the limbs, cardiac weakness, polinevrity, when expressed adverse events emetinom treatment must end.
Method of issuance: powder; 1% solution in 1 ml ampoule.
Storage: List B. Powder-well ukuporennoy packaging keeps out of the light; Ampoule in sheltered from the world scene.
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