Dopan (dopanum)


DOPAN (Dopanum). 5-[bis - (b-Hloretil-) - amino] -6-methyl Uracil.
     Synonym : Chlorethylaminouracil.
     White or white with a yellowish-gray shade melkokristallichesky powder, bitter-tasting, odourless. Almost nerastvorim in the water, little is soluble in alcohol.
     On chemical structure of the body and close to embihinu.
     Applied with chlamydia, mieloleykoze, (with enlarged spleen), chronic lymphoblastic.
     Assign inside after eating dose of 6-10 mg every 5 days (for children 0.1 - 0.2 mg / kg). The course of treatment consists of 5 to 7 receptions drug.
     In chronic mieloleykoze appoint 12 mg 1 - 2 - 3 times through April day, then reduce the dose to 10 mg with the same intervals. The total dose of treatment is 30-130 mg strength on drugs, especially from the reaction of patient blood.
     Possible complications and side effects in the application dopana similar to those that can occur when applying embihina (except those related to the injection).
     Prevention and treatment side effects are basically the same as when applying embihina.
     Dopan on is not suitable for chlamydia, leaking in the face of weak, kostnomozgovogo blood, in particular the level of leukocyte below 4, 5 x 10 9 / L and platelets less than 150 x 10 9 / L.
     Application dopana contraindicated for acute leukemia, rapid and acute limfogranulemetoza as well as chronic mieloleykoze with acute illness, rapid development of gemotsitoblastov blood and progressive anemia.
     Product : pills to 0,002 grams (2 mg) in a package of 35 pieces.
     Storage : List A. dry place.

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