DOTSETAKSEL (Docetaxel).

     The complex organic compounds (C43H53NO14), with structural elements of similarity with paklitakselom. Both compounds are derived benzolpropanoevoy acid and contain molecules fenilizoserina group.

     Synonym : Taksoter, Taxotere.

     White or almost white crystalline powder. Nerastvorim water.

     Like paklitakselu has cytostatic (antitumor) effect. Close to him on the operation.

     Applied with breast cancer (including metastaziruyuschy) nemelkokletochnom cancer light, ovarian, stomach; Head and neck tumors.

     Enter vnturivenno slowly (within 1 hour) in the dose of 100 mg / m 2 1 every 3 weeks. When expressed side effects dose reduced to 50-75 mg / m 2.

     Solution for infusions prepared from concentrate, stretched its isotonic (0.9%) solution of sodium chloride or 5% glucose solution.

     Before the introduction of a drug or drugs sedation protivogistaminnymi glyukokortikosteroidami.

     Possible side effects are the same as those paklitaksela.

     Product : 4% concentrate for infusion solutions in bottles of 7 and 15 ml complete with a solvent (water solution of ethyl alcohol).

     Storage : List B.

Materials allowed to copy only with the active hyperlink to the handbook of medicines