DIZOPIRAMID (Disopyramidum) *. 4-Diizopropilamino-2- 12-61 (2-piridil) - butiramid (phosphate).

     Synonyms : Korapeys, Palpitin, Palpitin, Ritmilen, Ritmodan, Corapace, Dicorantil, Dicorynan, Dimodan, Disopyramide, Korapace, Korapeis, Norpace, Palpitin, Ritmilen, Ritmodan, Rythmilen, Rythmodan, Rythmodul and others.

     As of close to quinidine; Complications related to a group I patients : it reduces the flow of ions across cell membranes in the museum, increases refrakterny period predserdiyah slows conductivity of predserdno- ventricular Beam (Beam Gisa).

     When applied predserdnyh and zheludochkovyh ekstrasistoliyah, spouses ventrikulyarnoy tachycardia. There are signs that the drug is more effective when tachycardia and ventricular arrythmia.

     Assign dizopiramid usually on the inside of 0.1 g (1 capsule), and in more severe cases, 0.2 g 3 - 4 times a day (with equal intervals).

     At first reception recommended "loading dose - 0.3 grams, and then choose the best indivi cord. Usually supporting dose-0.1 g 3 - 4 times a day.

     There are several other schemes of application, but not significantly different from that.

     For edema Cumulative departments dizopiramid injected dose of 50 to 150 mg.

     Dizopiramid complications is a very effective drug, but in its application could experience different side effects.

     Some of them are inherent in the drug expressed antiholinergicheskim of : dry mouth, a breach of accommodation, difficulties urine emit etc.; Others, with the possibility of oppression sokratimosti miokar so, the decline (in high doses) AD. There are increasing cases of arrhythmia. There may be headache, dizziness, allergic reactions.

     Contraindications : atrioventrikulyarnaya blockade sharp aetiology, expressed heart failure, kardiogenny shock.

     In violation of the functions of the kidneys and liver dizopiramida dose should be reduced ( "loading dose and no more than 0.2 grams in the future to 0.1 g at long intervals). Caution is needed in case volume in the preceding drugs slowing the pulse (amiodarone, etc.).

     Method of issuance : capsules to 0.1 g in a package of 40 and 100 pieces; Injection (1%) in ampoules to 5 ml (50 mg).

     Storage : List B.

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