DIGIDROTAHISTEROL (Dihydrotachisterolum). Methyl-24-9, 10-Seko, 5, 7, 22-K holestatrien- b-ol, or methyl-24-9, 10-seko-10- a holestratrien E-5, E-7, 22 E.-ol - 3 b.

     Synonyms : Tahistin, Anlitanil, Antitetanin, Atecen, Dichysterol, Dihydrotachisterol, Dihydrotachysterin, Dygratyl, Manipal, Parterol, Tachidon, Tachystin, Tachystol, Tetilan and others.

     Clear crystals or a white crystalline powder. Almost nerastvorim in water, soluble in alcohol.

     On chemical structure similar to ergokaltsiferolu (see). Has the ability to regulate the exchange of calcium and phosphorus. In some diseases with a violation of pesticides limestone exchange, increasing intake of calcium in the intestines and remove phosphorus from urine. Vitamin D activity unlike ergokaltsiferola no.

     When applied gipoparatireoze (idiopathic and aftercare), and other diseases involving the violation of pesticides limestone exchange, including gipokaltsiemicheskih convulsions, tetanii, spazmofilii, allergic skin reactions, etc.

     Is inside a 0.1% solution in oil (1 mg preparation of 1 ml) after food drops to 20 (0.5 mg) three times a day, every day; In severe cases, with steadily reduced content of calcium in the blood to 30 droplets (0.75 mg) three times a day. At 7 - 10-day treatment with concerns over the effect of supportive therapy : 20-60 drops (0.5 -1, 5 mg) per day 1 to 3 times a week.

     Dose individualiziruyut depending on the condition of the patient and content of calcium and phosphorus in the blood, which is set up to care for 5 to 7 days after the start, and then 1 to 2 times a month.

     In the case of a patient appointments digidrotahisterol calcium products can be used in smaller doses.

     Of the side effects can occur.

     Contraindicated in high content of calcium in the blood.

     Product : 0.1% solution in oil (Solutio dihydrotachisteroli oleosa 0.1%) transparent oily liquid from light yellow to yellow to orange glass bottles to 10 or 50 ml.

     Storage : List B. In the dark place at a temperature of not more than +5  C.

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