Digidroergotoksin (dihydroergotoxinum)


DIGIDROERGOTOKSIN (Dihydroergotoxinum).
     Digidrirovannoe amounts derived alkaloids group ergotoksina (ergokristina, ergokornina, ergokriptina), close to the structure and pharmacological properties of digidroergotaminu.
     Available in a metansulfonata (mezilata).
     Synonyms : Redergin, Sekatoksin, Ergotoksin DG, Alkergot, Circanol, Clavor, DH-Ergotoxin, Erginemin, Ergocomb, Ergodibat, Ergohydrin, Ergoloid mesylat, Ergomed, Ergoxyl, Hyderan, Hydergin, Optamine, Redergin, Redergot, Secamin, Secatoxin, Trigot, Vasolax and others.
     For medical use of the form of tablets and solutions.
     Pills "Redergin (Ta bulettae" Redergini "0,0015) contain 0.0015 g (1.5 mg) digidroergotoksina metansulfonata (synonym : Ergoloid mesilate, E rgoloid mesylate).
     Assign an adult as sosudorasshiryayuschego funds in violation of cerebral circulation, with migraines, and the impact of craniocerebral trauma, as well as violations of peripheral blood : Burger illness, disease Reynaud, with transitory hypertension, circulatory violations in retinal eye when kohleovestibulyarnom syndrome, etc. .
     Before taking food to one pill three times a day. Usually take long : from 3 - 4 weeks to several months, depending on the severity of the disease, efficiency, portability.
     Abroad digidroergotoksina Methanesulfonate (DH- rgotoxin E) was also issued in the form of drops for admission into and solutions for parenteral use.
     When hypertension and peripheral circulatory disorders beginning with the appointment of five drops of the drug inside three times a day, then increase the dose every day for 2 to 3 drops in the admission of up to 20-40 drops three times a day. The course of treatment with hypertension still 3 to 4 months; In peripheral vascular spasm-15 - 20 days. In spastic migraines appoint five drops three times a day in the early days, then increase the dose to 20-25 drops three times a day.
     In severe violations of peripheral blood type intramuscularly, or intravenously into the skin (drip) and 1 - 2 mL injection solution (1 - 2 capsules of 0.3 mg).
     In endarteriite happened vnutriarterialno 1 - 2 capsules (0.3 0.6 mg) per day. Enter the method electrophoresis (with the positive pole) and 1 - 2 capsules (0.3 - 0.6 mg) per day.
     Method of issuance : in ampoules to 1 ml (0.3 mg) in a package of 50 vials; In vials of 50 ml (1 mg in 1 mL).
     Storage : List B. In the dark place at a temperature of not more than + 25 'C.

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