DIGITOKSIN (Digitoxinum).

     Glikozid obtained from the different types of Foxglove (Digitalis purpurea

     L., Digitalis lanata Ehrh. etc.).

     C inonimy: Cardigin, Carditoxin, Cordalen, Cristapurat, Cristodigin,

     Digimerck, Digitin, Digitoxin, Digitoxinol, Digitoxosidum, Digotin,

     Purodigin and others.

     The white crystalline powder. Almost nerastvorim water ma-Members of alcohol.

     He is the most active glikozidom purpurovaya digitalis; Help Contents contained in woolly digitalis and other digitalis; 1 g digitoksina contains 10000-8000 or 1911-LED 2271 KED. Relatively quickly and almost completely absorbed from the gastrointestinal tract. Day satisfaction incipient through 2 - 4 h after administration, and the maximum effect was using 8 - 12 hours It has expressed strong cumulative effect.

     Assign mainly with chronic heart failure, which requires long-term care, particularly in the inclinations of tachycardia.

     Dose and duration of treatment should be strictly individual; In connection with the cumulative properties can be relatively easy to develop side effects related to overdoses.

     Accepted digitoksin inwards in the form of tablets containing at 0.0001 g (0.1 mg) drugs. Usually given in the early days of 0,6-1, 2 mg 'per day (4 reception at 6 h), the first dose is 1 / 3 to 1 / 2 day (Daily doses sometimes exceed the highest daily dose of GFH. ); to achieve therapeutic benefits of umenshayuot, selecting individual ness supporting dose, usually 0.1-0.06 mg (1 - 1 / 2 tablets) 1 to 2 times a day or through 1 - 2 - 3 days.

     For patients with dyspepsia events or stagnation in the ascites digitoksin vein can be used as a candle containing at 0.00015 grams (0.15 mg) glikozida (Suppositoria Digitoxini 0.00015). Enter usually in the rectum and 1 - 2 1 - 2 candles every day during the first 2 to 5 days, followed by dose reduction to 1 - 2 candles a day. In these cases, the dosage should also strictly collected individually.

     Higher doses digitoksina adults inside: single 0.0005 g (0.5 mg), 0,001 g daily (1 mg).

     When selecting doses side effects usually do not.

     In developing side effects dose reduced, and if necessary, stay es receive further preparation.

     Prior to the appointment digitoksina must determine whether the patient has not received immediately before this (last 10 to 14 days), others by serdech glycosides. In such cases, care should be taken to avoid cumulative phenomenon. Therefore, a suspension (10 to 14 days), after digitoksina appoint other cardiac glycosides.

     Contraindications-see common contraindications for use by serdech glycosides.

     Method of issuance: pills to 0.0001 g (0.1 mg) and candles to 0.00015 grams (0.15 mg).

     Storage: List A. In a cool, sheltered from the world scene.

     R p. : Ta b. Digitoxini 0.0001 N.10

     D.S. At 1 1 tablet every day (for supportive therapy)

     R p. : Supp. cum Digitoxino 0.00015 N.10

     D.S. On 1 January candle every day

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