DIKAIN (Dicainum) 2-Dimetilaminoetilovogo parameters butilaminobenzoynoy acid ester hydrochloride.

     Synonyms : Amethocaine, Anethaine, Decicain, Felicain, Foncaine, Intercain, Medicain, Pantocain, Pontocaine hydrochloride, Rexocaine, Tetracaini hydrochloridum, Tetracaine hydrochloride, etc.

     The white crystalline powder and odourless. The easily soluble in water (1:10), alcohol (1:6).

     Solutions are sterilized with 100 'C for 30 min; Solutions adds to stabilize the solution of hydrochloric acid to pH 4, 0, 6, 0.

     Dikain-strong mestnoanesteziruyuschee means far superior to activity novocaine and cocaine, but with high toxicity (2 times toksichnee cocaine and 10 times-novocaine), it should be used with caution.

     Dikain used only for surface anesthesia.

     In ophthalmic practice used in a 0.1% solution in the inner pressure measurement (one drop of 2 times at intervals of 1 2 min). Anesthetic usually develops in 1 to 2 minutes. Removing foreign bodies and rapid intervention applied 2 to 3 drops of 0.25 - 0.5-1% or 2% solution. After 1 to 2 minutes develops expressed anaesthesia. It should be borne in mind that solutions containing more than 2% dikaina can damage the cornea epithelium and an expansion konyunktivy receptacles. Usually, anesthesia surgical intervention in in front of a 0.5% solution. To lengthen and strengthen the anaesthetic effect adds 0.1% solution via (3 - 5 drops to 10 ml dikaina).

     In keratitis dikain not apply.

     In ophthalmic practice if necessary prolonged anesthesia using film with eye dikainom (Me mbranulae op hth and lmicae with Dicaino um). Each film contains 0.00075 grams (0.75 mg) dikaina. The foundation serves biorastvorimy polymer films.

     Dikain also used for the surface anesthesia in otorinolaringologicheskoy practice in certain operational intervention (piercing gaymorovoy procedure, the removal of polyps, konhotomiya, operations at the middle ear). The rapid intake dikaina minute shell respiratory tract should be very careful in its application and carefully monitor the patient. Children under 10 years dikainom no anesthesia. For older children, use no more than 1 to 2 ml of 0.5-1% solution in adults - to 3 ml of 1% solution (sometimes sufficient 0.25 - 0.5% solution), and only when absolutely necessary, or 2% 3% solution. By solution dikaina (in the absence of contraindications to the use of substances sosudosuzhivayuschih) adds 1 to drop 0.1% epinephrine hydrochloride solution for 1 - 2 mL dikaina.

     Instead dikaina preferable to use less toxic local anesthetics (lidocaine, piromekain etc.).

     Higher doses dikaina anesthesia for adults with upper respiratory tract infections - one 0,09 g (3 ml of 3% solution).

     Dose dikaina not exceed avoid severe toxic events. The literature describes cases smertelnih outcomes associated with overdose and wrong dikaina reception.

     Dikain contraindicated in children less than 10 years old and the general condition of patients.

     With dikainom instruments and syringes must not contain residual alkali, as dikain in the presence of alkali falls in the sludge.

     Method of issuance : powder and film with the eye dikainom (30 pieces in penalah- dosing).

     Storage : A. In a list ukuporennoy packaging.

Materials allowed to copy only with the active hyperlink to the handbook of medicines