Klodronat sodium (clodronate disodium)


KLODRONAT SODIUM (Clodronate disodium).
     Dinatrievaya dihlormetandifosfonovoy acid salt.
     Synonym : Bonefos, Bonefos.
     It stops bone resorption.
     Applied to reduce bone damage and pain to osteoporosis in cancer patients treated (with multiple myeloma and malignant tumors with metastases in the bone).
     Assign intravenously and inside.
     In the first 3-5 days injected (drip) of 0.3 g (3-5 mg / kg) in 500 ml isotonic sodium chloride solution, or 5% glucose in the day. Then take the interior of 0.8 g (2 capsules) three times daily rates for 60 days.
      With the possible proteinuriya veins; When administered, gastrointestinal disorders.
     Method of issuance : capsules to 0.4 g (400 mg) (N. 100); 6% solution (concentrate) in 5 ml ampoules.

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