TSIPROFLOKSATSIN (Ciprofloxacinum; Ciprofloxacine). 1. Tsiklopropil-6- fluoro-1, 4-digidro-4- Okseo (1-piperazinil) -3 - hinolinkarbonovaya acid.

     Issued as hydrochloride, and lactate.

     Synonyms: Kvintor, Tsipro, Tsiprobay, Arflox, Ciplox, Ciprinol, Cipro, Ciprobay, Ciprobid, Ciproran, Ciproxin, Quintor and others.

     According to the chemical structure of the closest to norfloksatsinu, which is replacing etilnoy team in the nitrogen atom of 1 hinolinovogo nucleus of tsiklopropilny Radikal.

     For antimicrobial spectrum of th basically similar to other ftorhinolonami, but it has relatively high; About 3 to 8 times more active than norfloksatsin.

     The product is effective in giving inside and parenteral transmission. When you receive inside, especially suffer, it is well absorbed. Peak concentrations in the blood plasma through a 1 - 2 h after administration of inwards and 30 min after intravenous. The half-about 4 hours Few associated plasma protein. Well into the organs and tissues, passes through cross the blood-brain barrier. About 40% is allocated from unchanged to the urine in 24 hours

     Indications for use mainly the same as for ofloxacin, and other pefloksatsina ftorhinolonov (respiratory tract infections, skin and soft tissues, bones and joints, gastrointestinal tract, including infection caused by salmonella, dysentery, and other pathogens kampilobakteriyami ; gonokokkovye infection, meningitis, postoperative infectious complications, sepsis and other structures inflammatory processes).

     The product vysokoeffektiven infection in the urinary track, the reception inside, it quickly enters the kidneys, provides long-term, has microbicides effect on Pseudomonas aeruginosa (predominant pathogenic cause of urinary tract infection complicated ways).

     The product is shown in the treatment of infections in cancer patients.

     Assign edition adults inside with uncomplicated urinary tract infection routes of 0,125 - 0.5 g 2 times a day with complicated urinary tract infections and infections of the respiratory tract-by 0.25 - 0.5 g 2 times a day; In more severe where to 0.75 g 2 times a day (if no parenteral treatment). The course of treatment is usually 5 to 15 days.

     In particularly serious infectious diseases and the impossibility of receiving pills inside, starting with intravenous drug preferably in the form of short-term acute (about ZO min). The finished solution (in vials) can be entered without cultivating or razvesti in isotonic sodium chloride solution, or 5% glucose solution. Concentrate pump solution (in 10 ml ampoule of 1% solution) to be a razvesti.

     In acute gonorrhea and uncomplicated cystitis in women appointed edition inside occasional dose of 0.25 g and intravenous dose of 0.1 d.

     The dose intravenous with uncomplicated urinary tract infection ways to 0.1 g 2 times a day, in other cases, 0.2 g 2 times a day. If the patient's condition improved, moving to pick up the drug inside.

     Possible side effects, precautions and contraindications see Ofloksatsin.

     Like others in this group, Medicines can assign children and adolescents with incomplete formation of the skeleton (15).

     Those elderly are smaller doses (depending on the severity of illness).

     Method of production: tablets, thickly coated in 0.25; 0.5 and 0.75 g; 0.2% solution in vials for Infusion of 50 and 100 ml (100 or 200 mg); 1% solution in 10 ampoule ml (concentrates to be production of).

     Storage: List B. In sheltered from the world scene.

Materials allowed to copy only with the active hyperlink to the handbook of medicines