Hlortrianizen (chlortrianisenum)

HLORTRIANIZEN (Chlortrianisenum). 1, 1, 2-Trianizil-2- Chloroethylene.
     Synonyms: Chlorotrianisen, Chlorotrisin, Chlortrianisoestrolum, Hormonisene, Merbentul, Metace, TASE, Trianisoestrol etc.
     The white crystalline powder and odourless. Almost nerastvorim in water, soluble in alcohol difficult.
     Hlortrianizen is a synthetic drug with estrogennoy activity. Admission is effective inside, malotoksichen. Relatively other synthetic oestrogen drugs (sinestrol, dietilstilbestrol), a more long-term. Apply primarily in the treatment of prostate gland cancer.
     Assign the interior of 0,012 g (12 mg tablet = 1) 2 - 3 times a day. Treatment for a long time. In addition prednisolone metastasizes apply: in the first three days to give 0,012 g (12 mg) three times a day for 4 to 5-day-to 0,012 g 2 times a day, then for a period of 7 days to 0.012 grams per day, and, since the 13rd of the day-to 0,005 grams (5 mg) per day for 40 days. The courses are one-two times a year.
     When breast cancer appoint 48 mg per day (1 tablet four times). Assign only patients in a late menopause and patients without a uterus (because of possible uterine hyperplasia mucosa).
     Higher doses for adults inside: single 0,012 g, 0,048 daily g.
     Hlortrianizen generally well tolerated by patients. He is nausea, vomiting, severe; Little expressed feminiziruyuschee effect (usually no ginekomastii); Emerging sometimes inflammation and pain in the dairy iron quickly pass.
     Form release: tablets, containing 0,012 grams (12 mg) hlortrianizena.
     Storage: List B. In sheltered from the world scene.

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