HINOTSID (Chinocidum). Metoksi-8- 6 - (4-aminopentil) - aminohinolina digidrohlorid.

     Synonyms: Quinocide, Quinocidum.

     Orange-yellow crystalline powder, bitter taste. Very easily soluble in water (1:2), it is difficult to alcohol.

     The product operates on paraeritrotsitarnye forms of malaria parasite, which makes distant relapse.

     Apply to prevent not only distant relapse trehi four malaria, but also those of malaria after personal chemoprophylaxis took place at high risk of infection. The product provides gamotropnoe effect on the sex of all kinds plazmodiev.

     In tropical malaria hinotsid can designate after the end of treatment hingaminom (or other drugs are not acting on gamonty P. falciparum) for the prevention of malaria through mosquito.

     Dose for treatment for adults or 0,3 0,28 g.

     In exchange dose of 0.3 grams of taking 0.02 grams per day for 10 consecutive days (Scheme 1); In exchange dose of 0.28 g of 0.02 g per day for 14 days (Scheme 2).

     Higher doses: adults inside: single day and was .03

     Children are hinotsid within 10 or 14 days in the following doses:

     The course of treatment

     Age, in a daily dose, g years

  10 days 14 days (Scheme 1) (Scheme 2)

     Before 1 0.0025 0.0015 1 - 2 0.005 0.0025: 3 - 4 0.0075 0.005 5-7 0.01 0.0075 8 - 12 0.015 0.01 13 15 0 02 0.015

     Over 15 0.03 0.02

     Preparation take 1 to 2 times after eating.

     Treatment scheme to have weakened 2 patients (preferably in the hospital).

     When you receive hinotsida may be side effects: nausea, headache, cyanosis lips and magazine floor, in some cases, signs of kidney and bladder, the drug fever; Possible small haemolysed, leukopenia or leykotsitoz. Adverse events taking place after preparation.

     For people with congenital deficiency in the blood enzyme glyukozo6- fosfatdegidrogenazy (genetic abnormality) is increased sensitivity to drugs group hinotsida (see Primahin) with a possible acute haemolysed.

     The relative contraindications: zaboleveniya blood and the blood, kidney disease, stenocardia. Hinotsid not appoint conjunction with other antimalarial drugs, as well as with his increasing toxicity.

     Must be careful in appointing a drug elderly and weak patients.

     Form release: tablets, coated skin (Tabulettae Chinocidi obductae), and 0.01 for 0,005 city

     Storage: List B. The well ukuporennyh banks dark glasses.

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