Henodiol (chenodiol)


HENODIOL (Chenodiol) *.
     Henodezoksiholevaya acid (Chenodesoxycholic acid).
     Synonyms: Henofalk, Aholit, Chelobil, Chendal, Chenochol, Chenofalk, Chenolith, Cholanorm, Fluibil, Henohol, Quenobilan, Soluston, Ulbenid and others.
     White or light yellow crystalline powder. Nerastvorim almost in the water. In physiological terms henodezoksiholevaya (as ursodezoksiholevaya) acid is synthesized in large quantities in the human intestine. The ability henodiola cause dissolution biliary stones associated with lower cholesterol education through inhibition mikrosomalnogo enzyme involved in cholesterol synthesis.
     Apply for dissolution neobyzvestvlennyh holesterinovyh stones small (diameter 20 mm), not found in conventional x study, especially if there is contraindicated for surgical intervention.
     Daily dose of 15 mg for an adult to 1 kg body weight (average 0.75 g).
     Assign 1 capsules (250 mg) morning and 2 capsules (0.5 g) evening. Sutochnnya maximum dose of 1, 5 g (6 capsules).
     The length of treatment depends on the size of stones over the disease, the drug portability (6-48 weeks, up to a year or more). When relapse take 1 - 2 capsules (0.25 - 0.5 g) during the three months or more.
     Using the drug can diarrhoea; In these cases, reduce the dose.
     Contraindications with stones found in the ordinary patient study, ie with a high content of calcium salts, when expressed as a violation of the bowel, gall kolike frequent, chronic hepatitis, liver cirrhosis, holangite and other serious diseases, liver and biliary moves in pregnancy.
     The product should not be appointed along with antacids (containing aluminum hydroxide) and anionitami (holestiraminom), in order to avoid deterioration of aspiration.
     Form release: 0.25 g capsules on the package of 100 pieces.

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