Tsefalotina sodium salt (cephalotinum-natriu)


TSEFALOTINA NATRIEVAYA SOL (Cephalotinum-natrium). 7 - (2-Tienilatsetamido) tsefalosporinovoy acid sodium salt.
     White or almost white crystalline powder. Easy soluble in water.
     Synonyms: Keflin, Averan, Cefalotin, Celorex, Ceporacin, Keflin, Lospoven, Rimigal, Synclotin, Toricecolin and others.
     Refers to tsefalosporinam first generation.
     It has a wide range of microbial action. A majority of gram and gram microorganisms. With regard to E. li, K l. s. neumoniae and salmonellosis, less activity anticipated.
     Gnoynovospalitelnyh apply to various diseases caused by sensitive to the action of microorganisms: sepsis, endocarditis, peritonitis, respiratory tract infections, genitourinary system, treat skin infections, soft tissue, bone, etc.
     Assign intramuscularly or intravenously. With the introduction vnutrimyshechnom detected in the blood after 30-60 minutes.
     Single dose for adults is 0.5 to 1, 0 grams daily-2-6 g (4-6 introductions). With heavy usage inflammatory processes single dose can be increased to 2 g (only intravenously), the interval between the introduction of 4 hours The maximum daily dose of 12 g.
     In renal failure dose tsefalotina reduced.
     Intramuscularly tsefalotin should impose a maximum dose of 0.5 grams due to the pain and opportunities infiltratov. If you want to use large doses, the drug introduced intravenously.
     Children appoint tsefalotina sodium salt in a daily dose of 50-100 mg / kg at intervals between injections 6 to 8 hours (3 to 4 introduction).
     For intramuscular injections dissolve ex tempore 0.5 -1, 0 g in 2 to 4 mL of sterile water for injection; Impose deep in the muscle. 2 g intravenously impose tsefalotina sodium salt, which dissolve in 10 mL of sterile water for injection, and add 250 ml of 5% glucose solution and isotonic sodium chloride solution. Enter at speeds 60 80 drops per minute.
     The product can cause allergic reactions and provide nefrotoksicheskoe effect. The latter is more common in patients with kidney function changes. In these cases, at least once a month to monitor kidney function.
     Perhaps tranzitornoe Enhancement aminotransferaz and alkaline fosfotazy blood. In a large intravenous doses might flebity and paraflebity, with the introduction vnutrimyshechnom-and the pain of making infiltraty place in the introduction.
     Contraindications to all tsefalosporinov.
     In the case of the simultaneous application of antibiotic-aminoglikozidami, poliksiminom B-more patients.
     Form release: in the hermetically ukuporennyh vials of 0.5; 1 and 2 g (Ser hal of tinum-natrium 0.5; 1, 0; 2, 0 r r on injectionibus).
     Storage: List B. In a dry, sheltered from the world scene at room temperature.

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