Tselekoksib (celecoxib)


TSELEKOKSIB (Celecoxib).
     4-[5 - (Metilfenil) -3 - (trifluoromethyl) -1 H pirazol-1- mud] benzosulfonamid.
     Synonym: Tselebreks, Celebrex.
     Provides anti-blood and action with a much reduced compared to the "normal" NPVS ultserogennom effect.
     Quickly absorbed, C max 2-3 h; Biotransformation are in the liver and be in the form of metabolites mainly through reductions.
     Apply with rheumatoid arthritis, distortive osteoartroze, sinovite jet.
     Assign the interior of 0.1 g 2 times per day or 0.2 g 1-2 times a day.
     Using the drug can be observed: dispersion, increased gastric ulcer disease and stomach cancer, gastrointestinal bleeding, breaches of sleep, a lack of clear, ringing in the ears, depression, anxiety, cough, increased blood pressure, disruption of kidney swelling, anemia, leukopenia , allergic skin reactions.
     Form release: capsules in 0.1 and 0.2 g (N. 10, 20).
     Storage: List B.

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