TSEFTAZIDIM (Ceftazidime) *.

     Tsefalosporinovy third-generation antibiotic for parenteral use.

     According to the chemical structure similar to other drugs in this group (see Tseftriakson).

     Synonyms: Kefadim, Mirotsef, Fortum, Cefortan, Ceftim, Fortam, Fortum, Mirocef, Panzid, Spectrum, Starcef, Tazidine and others.

     Issued in the form of white powder to yellowish color ampoule containing at 0.25; 0.5; 1 and 2 g tseftazidima with sodium carbonate (1, 18 mg / g tseftazidima 1). Adding water soluble product to form gas bubbles formed injection.

     Enter tseftazidim intramuscularly and intravenously. Both methods of quickly achieved the highest concentration of the drug in blood plasma (after 5 to 10 min after intravenous through 30-45 minutes after vnutrimyshechnogo introduction).

     The product is the long-term remains in the body, not product devoted mainly (80-90%) unchanged to the kidney in 24 hours Easily into the organs and tissues (for bone tissue), alternative is for the sputum, sinovialnuyu, blood, peritoneal fluid in the tissue fluid and the eye through the placenta barrier, badly damaged through cross the blood-brain barrier.

     Tseftazidim is a broad-spectrum antibiotic. Effective with infections caused by Escherichia sticks. Apply in septitsemii, peritonitis, meningitis, severe respiratory tract infections, urinary tract infections ways, skin, soft tissues, bones and joints, gastrointestinal tract, etc.

     The dose for adults is usually 1 g every 8 hours or 2 g every 12 hours (with heavy infection-to 6 grams per day). In less severe infection and urinary tract infection routes designated as a rule, 0,5-1, 0 g every 12 hours

     Patients with the functions of the kidneys, tseftazidima reduced dose (1 g every 12 hours and up to 0.5 g every 48 hours).

     Children, depending on age and severity of the disease, enter the product in smaller doses: the age of 2 months-25-50 mg / kg / day (2 admission), over 2 months-50-100 mg / kg / day .

     Possible side effects and contraindications basically the same as for other tsefalosporinovyh antibiotics.

     Form release: in vials of 0.25; 0.5; 1 and 2 of solutions prepared just before the introduction (in isotonic sodium chloride solution, or 5% glucose solution). We should not confuse one with a syringe solution tseftazidima aminoglikozidov solutions.

     Storage: at a temperature of not more than 25 "C.

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