TSEFPIROM (Cefpirom).

     Synonym: Keiten, Keiten.

     Tsefalosporinovy fourth generation antibiotic.

     According to the chemical structure is similar to the partial tseftazidimom (see). Is quaternary ammonium compounds. Because of the one molecule positive and negative charges as "tsvitternoe" connection. Like tsefmetazolu (see), contains molecules metoksigruppy (-OCH3). I think that these particular buildings tsefpiroma allow it to penetrate through the membrane gram bacteria to ensure the sustainability of? - Laktamaz and a wide range of antibacterial activity.

     Vysokoeffektiven against gram and gram aerobic and anaerobic microorganisms.

     When you receive inside poorly absorbed, but with the introduction of intravenous quickly enters the different organs and tissues, the blood in therapeutic concentrations over 12 h, which gives him authority to impose two times a day; In spinal fluid penetrates poorly; Devoted mainly kidneys, small quantities of bile.

     Apply with heavy infection of lower respiratory tract, urinary track, abdomen, skin, soft tissues, bones and joints, sepsis, and other surgical infection

     In connection with a broad spectrum antibacterial activity and high efficiency is recommended for use in hospitals and unsafe conditions, including "empirical therapy" (to identify the cause of infection). Can be combined with other antibacterial drugs.

     Enter in the form of intravenous drip infusions (30-60 minutes) or bolyusno of 1-2 g per 12 h (patients with impaired kidney function-0,5-1 g / day).

     The product is usually well tolerated by. There diarrhoeic phenomenon violation of liver and kidney functions, leukopenia, neutropenia, allergic reactions, flebity place in the introduction.

     Form release: powder for injection solutions in vials of 0.25; 0.5; 1 and 2 years

     Storage: List B.

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