Pentil 1-(5-deoksi-? -D- Ribofuranozil) -5 - fluorine-1, 2-digidro-2- okso-4- pirimidinkarbamat.
Synonym : Kseloda, Xeloda.
Like ftorafuru is prolekarstvom ftoruratsila (turning it in Tumor Cells).
Antimetabolit pirimidina (ingibiruet timidilatsintetazu).
Quickly and completely absorbed in the digestive tract, C max at 1.5 h, T? - 3-4 h is biotransformation in the liver and Tumor Cells, presented mostly kidneys.
Applied with large bowel cancer, breast, ovary.
Assign inside (after 30 minutes after eating) of 2.5 g / m 2 per day (2 admission) within 2 weeks, a second course after 1 week.
Possible side effects : neutropenia, thrombocytopenia, anemia, dry mouth, anorexia, diarrhoeal phenomenon parestezii, swelling, watering, hyperpigmentation.
Contraindications : pregnancy, breast-feeding.
Product : pills to 0.15 g (N. 60) and 0.5 g (N. 120).
Materials allowed to copy only with the active hyperlink to the handbook of medicines