KALTSITRIN (Calcitrinum).

     The drug made from kaltsitonina received from schitovidnyh glands of pigs. Earmarked for parenteral use.

     Producing a sterile powder dried white. Aqueous solutions drug transparent, colourless; PH 3 0 - 6, O. activity determined by biological and expressed in units of (ED). At 1 mg product contains at least 60 ED.

     Indications for use are the same as for kaltsitonina.

     Kaltsitrin impose subcutaneously or intramuscularly. Diluted dissolve in sterile water for injection immediately before use. Before treatment, the contents of calcium in the blood and skin samples to impose one-intracutaneously ED kaltsitrina in 0.1 mL solvent. Patients with skin reactions expressed at kaltsitrin (intense erythema, swelling) are not treated.

     The preparation to enter one time a day every day during the month of July, with a break every day or every other day for 2 to 3 months. Treatment started in a hospital and continue to out-patient basis.

     Athletes with pathological area of bone, patients with slow-seam fractures, in light cases of osteoporosis in neendokrinnyh diseases requiring long-term use of glucocorticoids, drug appoint ED 1 a day.

     In systemic skeletal defeat moderate, as well as traumatic and wounding drug appoint two 3 - ED in the day, in the case of severe systemic and focal lesions in the skeleton - ED 5 a day.

     Re-injection rate to at least 2 months, in cases of mild and gravity-usually 6 to 12 months.

     Along with kaltsitrinom to designate the interior of drugs calcium (glycyrrhizinate or calcium gluconate to 4 to 6 g / day).

     During treatment kaltsitrinom possible allergic reactions in the injection site, tidal blood-to-face, raising blood pressure. In these cases, make a break for treatment for 2 to 3 days. The emergence expressed repeated calls for the abolition of drug reactions.

     Introduction kaltsitrina in high doses (more than 5 ED for injection) may be accompanied by nausea and sometimes vomiting.

     If overdose or sensitivity to patient preparation develop signs gipokaltsiemii (parestezii, muscle car), then dropped to introduce calcium gluconate.

     Contraindications to gipokaltsiemii, pregnancy and breastfeeding.

     Product : sterile dried powder of 10 and 15 ED in hermetically ukuporennyh bottles.

     Storage : List B. In dry, the dark place at a temperature no higher than 20 ° + Solution drug store with a temperature of 4 + X is not more than 5 days.

     While the application kaltsitrina by inhalation (1 - 2 ED 1 - 2 mL of distilled water; In the course of 8-10 inhalation) with obstructive bronchitis (in the adjuvant therapy). Explain antiinflammatory effect and anti actions related to the inhibition degranulyatsii fat cells and other processes.

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