CALCIUM DOBEZILAT (Calcii dobesilas). 2, 5-Dioksi- benzolsulfonata calcium dihydrate.

     Synonyms : Doksium, Dobesifar, Dobesilat-calcium, Etruval, Romiven, Stifarol, Tricatine and others.

     White or white or rosy shade kremovatym crystalline powder. The easily soluble in water. Gigroskopichen.

     The structure and action close to etamzilatu; Several more have expressed a normalizing effect on vascular permeability increases capillary resistance, and improves lymphatic drainage function receptacles aggregation reduces the number of platelets, reduces the viscosity of blood. Has some antigemorragicheskoe effect.

     The drug is slowly absorbed from the gastrointestinal tract; The maximum concentration in the blood after receiving inside there after 5 to 6 hours As ionized compound barely penetrates through the blood-brain barrier. Write mainly kidneys within 24 hours

     The operation is linked to some extent with the increasing activity of platelets, reducing activity plazmaticheskih kininov (bradikinina; See Parmidin), as well as a direct influence on endotely receptacles.

     Calcium dobezilat applied in various diseases involving violations of vascular permeability and microcirculation disorders, including diabetic retinopathy and other angiopatiyah, mikroangiopatii with posttromboticheskom and haemorrhagic syndrome, varicose veins and prevarikoznyh of events with the swelling tissue surface flebitah, trophic ulcers, etc. .

     Is inside during or after eating in one pill (0.25 g) 3 - 4 times a day. The course of treatment for 3 to 4 weeks to several months, depending on the effect. Courses of treatment can be repeated if necessary.

     When intake of calcium dobezilata possible diarrhoeal phenomenon, allergic skin reactions. In these cases, if necessary, reduce the dose or stop receiving the drug.

     Contraindicated in pregnancy.

     Product : pills to 0.25 grams in a package of 50 and 100 pieces of glass lighting banks.

     Storage : List B. In dry, the dark spot.

Materials allowed to copy only with the active hyperlink to the handbook of medicines