BUSPIRON (Buspirone).

     8-[4-[4 - (2-Pirimidinil) -1 - piperazinil] - butyl] -8 - azaspiro- [4,5] Dean-7, 9-dione.

     

     Synonyms : Buspar, Spitomin, Bespar, Buspar, Spitomin

     Is benzodiazapine of tranquilizers electoral anksioliticheskim (protivotrevozhnym) action has no convulsants and miorealaksantnymi properties is less pronounced sedative effect.

     Mechanism of action not clear.

     When ingestion rapidly and completely absorbed, while the bioavailability is only 4%, C max-min 40-90, T1 / 2-hour 2-3; Under intense biotransformation in the liver with the formation of active metabolite (1-pirimidinilpiperazina).

     Used primarily for the treatment of serious conditions.

     Assign the inside, starting with 0,005 grams (5 mg) 2-3 times a day, gradually increasing the dose of 0,005 grams (5 mg) every 2-3 days before impact. The maximum daily dose of 0.06 g (60 mg).

     The drug is usually well. There neuralgia, chest pains, depression, muscle weakness, dizziness, increased body temperature, a sense of anxiety and rarely "fog" of, insomnia, hallucinations, etc.

     The drug is not suitable for serious violations of the liver and kidneys.

     Buspiron not encouraged to nominate children and adolescents under the age of 18 years (due to lack of sufficient data).

     Product : pills to 0,005 and 0.01 g (5 and 10 mg) (N. 10.60).

Materials allowed to copy only with the active hyperlink to the handbook of medicines