Buskopan (buscopan)


BUSKOPAN (Buscopan).
Butilskopolamin or N - (1S, 3S, 5R, 6R, 7R, 8S) - epoksi-8- butil-3- / (S) - tropil- Oxy / tropana bromide.
     Synonyms : Butilskopolamin bromide, Giostsina butilbromid, Giostsin- H butilbromid, Spanil, Alcopan Amisepan, Antispaspin, Brobutil, Buscol, Buscolamin, Buscolysin, Buscopin, Buscoridin, Butylscopolamini bromidum, Butylscopolammonium bromidi, Hyoscine-N-butylbromide, Scopolamine butylbromide, Spanil, Spasmalexin, Tirantil, Toscopan.
     The white crystalline powder. The easily soluble in water.
     Semi giostsiamina derivative.
     Has expressed election m holinoliticheskoe effect. Like other quarternary ammonium compounds are poorly absorbed in the digestive tract, not penetrate through the blood-brain barrier.
     Effective with cramps gladkomyshechnyh bodies, in some cases exceeds the new engine and papaverin.
     Applied to treat spastic pain conditions in zhelchnokamennoy and urolithiasis, chronic cholecystitis, gipermotornyh psoriasis oesophagus, gall bladder and Pepsi ways in gastric ulcers and duodenal ulcers, irritation bowel syndrome, dismenoree, and the later disclosure Wrench uterus during childbirth, when pilorospazme infants.
     Using x-rays and blood, if necessary, to reduce the tone and peristaltiku stomach and intestines.
     Applied inside, rectally and parenteral.
     Inside take on 0,01-0,02 g (10-20 mg) 3-5 times a day, squeezed water.
     Rectally designate adults and children (over six years) for the 1-2 jobs 3-5 times a day.
     In acute stroke spastic impose more subcutaneously, intramuscularly or intravenously 0.02 g (1 content capsules) 1-2 times a day.
     Buskopan usually well. Antiholinergicheskie side-effects (dry mouth, tachycardia, a delay of urination) are rare, they expressed a lesser extent than in the application of atropine, and being alone.
     The drug is contraindicated in glaucoma and isolationist prostate gland.
     Method of issuance : Bean to 0.01 g (N. 10); Jobs rektalnye to 0.01 g (N 5); 2% solution of 1 ml ampoules.

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