BUFENOKS (Buphenoxum). 3-Butilamino-4- fenoksi-5- sulfamoilbenzoynaya acid.

     Synonyms : Bufenox, Bumetanid, Burinax, Burinex, Fluxil, Jurinex, Primex, Segurex and others.

     White amorphous or melkoigolchaty powder

     Almost nerastvorim in water, soluble in alcohol difficult.

     The structure and action close to furosemide. Provides fast approaching and with a short diureticheskoe natriyureticheskim and kaliyureticheskim effect.

     The drug is well absorbed from the stomach. Increased urine withdrawal begins in the first hours after admission and continued into 4 to 6 hours Indications for use mainly the same as for furosemide. Effective in smaller doses.

     Bufenoks appointed interior (usually in the morning before breakfast). Dose choose individually depending on the severity of the disease and provided effect.

     Under the dose of 0,001 g. In the absence of the desired effect of increasing to 0,002 g.

     Higher daily doses of 0,006 grams (6 mg). Better to take pills for 3 to 5 days, then move on to intermittent reception for 0,001 - 0,002 grams 1 every 2 or 3 days. Duration and the total length of treatment depends on the severity and nature of the disease, receive benefits and endurance.

     When expressed dropsical syndrome usually designate a row in the 3 - 5 days, then take 1 to 2 mg (0,001 - 0,002 grams) 1 2 -3 times a day.

     Intravenously and intramuscularly bufenoks apply only in a hospital if necessary, rapid effect (swelling in the lungs, brain, etc.) as well as difficult swallowing and violating intake.

     Best single dose of parenteral introduction of 0.5-1 mg (2 to 4 ml of 0.025% solution).

     In introducing non slowly (over 2 to 3 minutes); The contents of capsules to throw 20 ml isotonic sodium chloride solution, or 5% glucose solution.

     If necessary, repeat injections through 4 - 8 hours

     The highest daily intake, with the introduction of parenteral 0,005 grams (5 mg).

     Possible side effects and contraindications are the same as for furosemide and dihlotiazida. During treatment is recommended to eat, rich potassium salt.

     Method of issuance : pills to 0,001 g (1 mg) in a package of 50 pieces; 0.025% solution (transparent colourless liquid) in 2 ml ampoules in a package of 10 vials.

     Storage : List B. In the dark spot.

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