BIKALUTAMID (Bicalutamide).

     (±) -4? - Cyano ?,?,?- triftor-3- [(para-fluorophenyl) sulphonyl] -2-methyl-meta laktotoluidid.

     Synonym : Kasodeks, Casodex.

     The white crystalline powder. Almost nerastvorim water poorly soluble in chloroform and ethanol, it is difficult to methanol, soluble in acetone.

     Androgenic receptor blockers.

     When ingestion rapidly and completely absorbed, T? at about 7 days; biotransformation exposed in the liver, presented with urine and faeces.

     Applied with cancer prostate gland.

     Assign inside of 0,05-0,15 g (50-150 mg) once a day, one day. Typically used in conjunction with gozerelinom (see).

     Possible side effects : diarrhoeal phenomenon Bitch, kserostomiya, reduced libido, peripheral oedema, provoking strokes and heart failure, gastric bleeding, depression, hyperglycemia, mialgiya, arthralgia, delay urination, allergic reactions, etc.

     The drug should not appoint women and children.

     Product : pills to 0.05 and 0.15 g (N. 28).

     Storage : List B.

     There are other inhibitors of 5-? - Reductase (epristerid-Epristeride etc.), operating like finasteridu and close to the structure.

Materials allowed to copy only with the active hyperlink to the handbook of medicines