Benzylpenicillin novokainovaya salt (Benzylpenicillinumnovocainum).
MONOHYDRATE novokainovoy benzilpenitsillinovoy acid salts.
Synonyms : Abbocillin, Benzylpenicillinum, Biocillin, Duracillin, Novocillin, Novocin, Procaini Benzylpenicillinum, Procillin and others.
The white crystalline powder odourless, bitter-tasting. Little is soluble in water. With water forms a thin slurry. Resistant to light. Easily destroyed when the effects of acids, alkalis and enzyme penitsillinazy.
On spectrum antimicrobial action is different from sodium and potassium salts benzylpenicillin.
Theoretical 1011 ED drug activity in the 1 mg. Virtually must contain at least 970 mg ED 1.
Features of the drug is slowly stripping and prolonged action in the intramuscular introduction.
After a single injection of a suspension, therapeutic concentration of penicillin in the blood continues up to 12 hours
The drug is only intramuscularly. Intravenous endolyumbalnoe introduction and is not allowed.
Enter 3 to 4 times daily. The average therapeutic dose for adults : single ED 300000, 600000 ED daily. The highest daily intake for adults 1200000 ED. Children under the age of 1 year to designate 50000 - 100000 ED / kg / day, over 1 year of 50000 - ED / kg per day. The daily dose for adults and children to give 1 - 2 admission.
To produce a drug suspension ex tempore : in a bottle containing salt of benzylpenicillin novokainovuyu dry, sterile syringe type 2 to 4 ml of sterile water for injection or isotonic sodium chloride solution and a bottle vstryahivayut intensively; The resulting suspension rapidly gaining syringe and impose deep in the muscle top the outer quadrant of the buttocks. Before introducing make sure that the needle is not named in the circulatory vessel. To use a thick needle injection (diameter 0.8 mm).
Possible complications and contraindications are the same as in the use of other drugs penicillin, as well as increased sensitivity to novocaine.
Product : in vials on 300000; 600000 and 1200000 ED.
Storage : B. list at room temperature.
Benzylpenicillin novokainovoy mixture of salt and sodium salt of benzylpenicillin sootnotenii 3:1 issued under the title "Novotsin (Novocinum) in hermetically ukuporennyh bottles containing 400000 ED (ED novokainovoy 300000 100000 ED salt and sodium salt benzylpenicillin) 800000 and ED 1.2 million.
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