AZELASTIN (Azelastine).

     4-[(4-Hlorfenil) methyl] -2 - (1-methyl geksagidro-1- azepin-4- mud H) -1 (2 H) - ftalazinon.

     Synonym : Allergodil, Allergodil.

     Lock N1- gistaminovye receptors and slowing degranulyatsiyu fat cells (prevents the release of histamine and other mediators allergies).

     Easily absorbed in the digestive tract and mucous membranes, T? about 20 h penetrates through gistogematicheskie barriers; kidney presented in the form of metabolites.

     Applied with allergic rhinitis and conjunctivitis (seasonal and year-round).

     Assign the interior of 0,002 grams (2 mg) on the night, 1-2 on the route-inhalation in a bow at 1-2 times a day, instillyatsii in each eye for one drop of 2-4 times a day.

     Possible side effects : using intranasal spray-drying and irritation of mucous nose, nasal bleeding and the violation of taste; When applying eye drops-konyunktivy anger and the bitter taste in his mouth.

       The drug is contraindicated in the first trimester of pregnancy and breast-feeding, the age of 4 years (eye drops), and up to 6 years (intranasal spray).

     When treating conjunctivitis should not wear contact lenses.

     Method of issuance : pills to 0,002 grams (2 mg); 0.1% intranasal spray in vials of 10 ml (0.14 mg / dose); 0.05% solution (eye drops) in vials 6 , and 10 ml.

Materials allowed to copy only with the active hyperlink to the handbook of medicines