ARTIKAIN (Articaine).

     Methyl ester methyl 4-[2 - (propilamino) propionamido] -2 - tiofenkarbonovoy acid.

      Synonyms : Alfakain, Brilokain, Septanest, Ubistezin forte, Ultrakain, Alphacaine, Ultracaine.

      White or white with a white crystalline powder kremovatym. Mg in water and alcohol.

      Provides quick and relatively long-term (1-3 h) mestnoanesteziruyuschee effect.

      In intramuscular introduction of C max-min 20-4, T? 40 min; biotransformation are in the liver, kidneys displayed.

     When applied irrigated, conductors, and lyumbalnoy spinal anesthesia.

     Ultrakain used mainly in obschehirurgicheskoy practice alfakain N and SP, brilokain in obschehirurgicheskoy and dental and ultrakain Dr. X and Dr. S Fort, septanest with contests in dental.

     In dentistry used in the operation of mucous lining or bones, the tooth pulp in teeth extraction, cutaneous osteosynthesis, kistektomii, mukogingivalnyh operations.

     For irrigated anesthesia using 1% solution artikaina (5-20 ml) with epinephrine (1:200 000), and without it, and conductors for the blockade and epidural anesthesia-1-2% solution (0,4-0,6 g) and spinal-5% solution (0,1-0,15 g), based on 10% glucose solution.

     The maximum single dose of 0.4 and 0.6 grams, respectively without and with added adrenaline.

     In applying artikaina possible side effects : headache, clouded in the eyes, diplopia, muscle car; In rare cases, a violation of conscience. Also likely allergic reaction-swelling and redness at the injection skin, swelling and other angionevrotichesky

     The drug is contraindicated in bronchial asthma, adults, zakrytougolnoy glaucoma.

     Method of issuance : 1% and 2% in the solutions for injection ampoules of 5 and 20 ml (Ultrakain); Injection containing artikaina 0.04 g (40 mg) and epinephrine bitartrata 1:200 000 (Alfakain N), or 1 : 100000 (Alfakain SP) in patronchikah (cartridges) to 1.8 ml; injection containing artikaina 0.06 g (60 mg) and epinephrine 1:100 and 1:200 000, 000, in patronchikah to 1.8 ml (Septanest with epinephrine); injection containing 1 ml artikaina 0.04 grams and 0,006 mg epinephrine (Ultrakain Dr. X), or 0,012 mg (Ultrakain Dr. X forte), in patronchikah 1, 7 ml.

Materials allowed to copy only with the active hyperlink to the handbook of medicines