ARMIN (Arminum).
Ethyl, para nitrofenilovy etilfosfonovoy acid ester.
Liquid yellow or dark yellow. Malorastvorim water. 0.01% solution is a colorless liquid transparent; pH 3, 5, 5, 5.
Armin belongs to the group of organic phosphoric acid esters (fosforganicheskih compounds - CSF).
Drugs in this group have strong anticholinesterase activity and irreversible cholinesterase inhibitors.
Effects caused by such substances, largely coincide with the effects of other anticholinesterase drugs (see Fizostigmin, Neostigmine, etc.), but they are much stronger and longer. In appropriate dose (or concentration), these substances have a strong toxic effects associated with the central and peripheral giperaktivatsiey holinergicheskih systems of the body.
Some substance of the group in connection with the consequent effect of a strong mioticheskim found use (in small concentrations) as a local mioticheskih and protivoglaukomatoznyh funds.
The main protivoglaukomatoznym preparation of this group is Armine. Fosfatol issued earlier drugs, hloroftalm, pirofos, hlofosfol excluded from the range of medicines.
Armin used as mioticheskogo and antiglaukomatoznogo funds in the form of eye drops in the concentrations of 0.01% (1 : 10000). Assign to drop 2 1 2 - 3 times a day. Armine, can be used in conjunction with other antiglaukomatoznymi drugs.
To avoid the common side effects associated with drug intake, it should be after each backfilling Armina chemical finger of lachrymal bag over 2 to 3 minutes, to prevent the solution in the lachrymal canal.
Possible side effects (with overdose and individually sensitivity), the same as in the application of other anticholinesterase drugs.
In some cases, the phenomenon can be observed mucous membranes eye irritations.
Product : 0.01% solution in 10 mL bottles.
Storage : List A. In the dark spot.
R p. : S G1. A rmini 0.01% 10 ml
D.S. Eye drops. On 1 - 2-Z drops 2 times a day (with glaucoma)
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